Asthma Acute
Conditions
Brief summary
COMPARISON OF EFFICACY OF HYDROCORTISONE AND METHYLPREDNISOLONE IN ACUTE SEVERE ASTHMA In this study Investigator will compare the efficacy of hydrocortisone and methyl prednisolone in acute severe asthma that will lead to final result and beneficial effects that will help in early resoloution of symptoms and help in preventing recurrence
Detailed description
investigator will compare the efficacy of hydrocortisone v/s methylprednisolone in management of patients presented with acute severe asthma in emergency. A local study was conducted in 2009, after that there is a big research gap exists at national level although international literature is available on the same but it can not be generalized to our population due to socio, geographic and economic differences so there is dire need to conduct this study this gives a strong rationale to implement in our settings
Interventions
DRUGMethylprednisolone,
No intervention required
Sponsors
University of Karachi
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Inclusion criteria
* Either Gender (18 to 50 years old) * Patient presenting to emergency department with acute severe asthma
Exclusion criteria
* Patients with critical illness or pregnant females. .Patient treated other than hydrocortisone and methylprednisolone. .Patients not willing to participate in study. * Life threatening asthma * Near fatal asthm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spirometry | 24 hours | Above will be check on arrival of patient to Emergency and post Managment |
| Blood pressures | 24 hours | Vital signs at initial presentation and post managment will be recorded Blood pressure in mm HG will be recorded |
| Respiratory rate | 24 hours | Respiratory rate at arrival and post managment will be considered Respiratory rate in Breaths/min |
| Heart rate | 24 hours | Heart rate beats/min will be checked |
| PEAK EXPIRATORY FLOW RATE | 24 hours | it wil be checked on arrival and post managment in Peak Expiratory Flow rate (force expiratory volume in 1 second and force vital capacity )will be examined |
Countries
Pakistan
Outcome results
None listed