Translational Cancer Observational Protocol

2014 Transizionali - Observational Study on the Occurrence of Relapses and on the Quality of Life in Patients Who Underwent Nephroureterectomy Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06169436

Enrollment

1250

Registered

2023-12-13

Start date

2014-07-17

Completion date

2064-07-17

Last updated

2023-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper Urinary Tract Urothelial Carcinoma

Keywords

Upper Urinary Tract Urothelial Carcinoma, Nephroureterectomy surgery, Relapse, Quality of life, Diagnosis and Treatment strategies

Brief summary

Observational study on relapse occurrence and on the quality of life in patients who underwent nephroureterectomy surgery

Detailed description

Monocentric prospective and retrospective observational study on the quality of life and on the pathological status in patients who underwent nephroureterectomy surgery. Oncological, psychological, sexual and quality of life-related data will be collected within a specifically created database that will allow us an easy and secure data extraction for the statistical analysis required by the clinical trial in terms of oncological relapse, clinical progression and improve the assistance and therapeutic strategy for each patient. Retrospective data for patients who underwent surgery between 1987 and today will be available in the form of clinical report stored in the hospital archives.

Interventions

PROCEDURENephroureterectomy

Removal of cancer mass by urether and kidney complete resection.

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years or older * Upper tract urothelial cancer diagnosis * Indication to cancer removal through nephroureterectomy surgery * Ability to read and sign the informed consent

Exclusion criteria

* Age \< 18 years * Absence of upper tract urothelial cancer * Inability to read and sign the informed consent

Design outcomes

Primary

Measure	Time frame	Description
Clinical progression data collection	50 years	Collection intended for the purpose of implementing diagnostic and therepautic strategies for the management of the disease in both the patient enrolled in the study and for future cases. Data will be collected in a dedicated internal database by means of medical records obtained during the patients' stay in the hospital and during follow up visits. The data collected includes anamnesis, data regarding surgery, laboratory exam and imaging exams.

Countries

Italy

Contacts

Primary ContactFrancesco Montorsi, MD.

montorsi.francesco@hsr.it02 2643 7286

Backup ContactFrancesco Fiorio, MSC

fiorio.francesco@hsr.it02 2643 6268

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026