Skip to content

The Long-term Course of Moderate Tricuspid Regurgitation

The Long-term Clinical Course of Moderate Tricuspid Regurgitation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06169345
Acronym
LOCOMOTRI
Enrollment
250
Registered
2023-12-13
Start date
2021-05-01
Completion date
2023-02-01
Last updated
2023-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tricuspid Regurgitation, Heart Failure, Echocardiography

Brief summary

To evaluate the long-term clinical outcome of a cohort of patients suffering from moderate tricuspid regurgitation (TR), regardless of its etiology.

Interventions

Echocardiographic follow-up

Sponsors

IRCCS San Raffaele
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 95 Years

Inclusion criteria

1. Patients with an echocardiographic diagnosis of moderate TR 2. Patients with echocardiographic and clinical follow-up information available at least 6-months after moderateTR diagnosis.

Exclusion criteria

1. Absence of an appropriate clinical and echocardiographic follow-up 2. A history of previous TV intervention (either surgical or percutaneous) 3. The presence of concomitant TV stenosis 4. Congenital heart disease 5. Left ventricular assist devices

Design outcomes

Primary

MeasureTime frameDescription
All-cause deaththrough study completion, an average of 2 yearsTime from diagnosis to all-cause death

Secondary

MeasureTime frameDescription
Cardiovascular (CV) mortalitythrough study completion, an average of 2 yearsThe occurrence of cardiovascular (CV) mortality (defined as death due to advanced heart failure, coronary ischemic heart disease, sudden cardiac death or due to stroke

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026