Acute Coronary Syndrome, Ischemic Stroke, Multi Vessel Coronary Artery Disease
Conditions
Brief summary
The goal of this observational study is to investigate the potential differences in thrombogenicity between black and white patients admitted with atherothrombotic events including acute coronary syndrome, multi-vessel coronary disease, and ischemic stroke. Participants will engage in laboratory testing and health outcome assessments.
Interventions
BEHAVIORALLife and Medication Recommendations
Based on obtained subjective and objective data from patient-filled questionnaire and laboratory testing respectively, lifestyle and medication recommendations will be provided for secondary prevention of cardiovascular and cerebrovascular diseases
Sponsors
University of Maryland
LifeBridge Health
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients ≥18 years of age admitted with ACS, AIS, or multi-vessel CAD * Competent mental condition to provide informed consent and able to participate in follow-ups
Exclusion criteria
* Pregnant women * Currently enrolled in an investigational drug or device trial * Undergoing treatment for neoplastic, autoimmune, or connective tissue disease * COVID-19 infection within 30 days of enrollment * Known history of hepatitis or HIV * Deemed unfit to participate according to the investigator * Known history of drug abuse * Known platelet count of \<100,000/mm3 * Hematocrit \< 25%
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Differences in Platelet Fibrin Clot Formation (MA,mm) | Baseline | Differences in Platelet Fibrin Clot Formation (MA,mm) Between Black and White Patients |
| Differences in Speed of Clot Formation (R, min) | Baseline | Differences in Speed of Clot Formation (R, min) Between Black and White Patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Major Adverse Cardiovascular Events Post Index Hospitalization | 3 and 12 months post index hospitalization | Major Adverse Cardiovascular Events (death, MI, stroke, unplanned target vessel revascularization, major bleeding) Post Index Hospitalization |
Countries
United States
Contacts
Primary ContactKevin Bliden, BS, MBA
Outcome results
None listed