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Acute Effects of Physical Activity on Cognition and Well-being in University Students

Acute Effects of Physical Activity on Cognition and Well-being in University Students: ActClass4Brain Project

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06168526
Acronym
ActClass4Brain
Enrollment
120
Registered
2023-12-13
Start date
2024-03-01
Completion date
2026-03-15
Last updated
2026-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Change, Well-Being, Psychological

Keywords

Young adults, Acute physical activity, Attention, Positive affect, Negative affect

Brief summary

Previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions. This highlights the importance of evaluating how physical activity can affect cognition and affective dimensions. However, to date, the dose of physical activity that could be most effective for these variables has not been established. This project aims to study the impact of acute physical activity on brain health in a university setting. Thus, this study will contribute to expand the current scientific literature on the acute effect of physical activity, a topic of great importance both in the educational field and from a public health point of view.

Detailed description

Students in the university stage face many changes in their lives. These changes, partly derived from academic activity, can cause alterations in their lifestyle and brain health (i.e., cognitive, emotional, and behavioural functioning). Due to the negative association of several indicators of brain health with academic performance during the university stage, it is of interest to promote strategies that can favour it. Among them, previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions. However, to date, the dose of physical activity (i.e., type, duration, and intensity) that could be most effective for these variables has not been established. Furthermore, previous studies in the matter have been carried out in laboratories and few investigations have analysed outside them the impact of acute physical activity on brain health in university classrooms. Therefore, expanding the current scientific literature on the acute effect of physical activity is of great importance in the educational field, since it would contribute to the design of active proposals aimed at improving brain health with positive implications for students' academic performance and quality of life. Accordingly, this project aims to carry out an acute physical activity intervention with different intensities and active breaks with students from the Jaume I University (Castellon de la Plana, Spain). More precisely, a total of 210 students between 18 and 24 years old will participate in the intervention. To achieve it, a randomized crossover study design will be carried out with the groups of participants compensated in terms of number and sex. Attention will be assessed using the d2-R questionnaire and emotional well-being will be assessed using the Positive and Negative Affect Schedule questionnaire. The tests evaluating attention and emotional well-being will be carried out before and after each condition. The experimental conditions will be: control group (quietly sitting), light intensity (40% VO2max), moderate intensity (63% VO2max), or vigorous intensity (100% VO2max) exercise, all lasting 16 minutes. In addition, an active break will be performed at the intensity of physical activity that proves to have the greatest benefits on cognition and well-being. It will include 12 blocks of 30 seconds of work, performing as many repetitions as possible, followed by 15 seconds of static rest. It will last last 9 minutes and will be conducted after a 2-hour lecture. During the active rest period, heart rate will be monitored using a heart rate monitor to register the intensity. Taking into account that the lifestyle of students is mainly characterized by the accumulation of prolonged periods of sedentary activity, introducing physical activity in the classroom represents an interesting opportunity for intervention from both an educational and a public health point of view.

Interventions

BEHAVIORALAcute physical activity

Regarding the first aim, participants will go through five different conditions using a within-participants cross-over design in a randomized order: control group (quietly sitting), light intensity (40% VO2max), moderate intensity (63% VO2max), or vigorous intensity (100% VO2max) exercise. All conditions will last 16 minutes and 15 seconds. The exercise conditions will be organized following an interval protocol, which includes 22 bouts of 30 seconds running at the established intensity with 15 seconds of passive rest between bouts. In addition, to achieve the second aim, the active break will be designed taking into account the intensity of physical activity that proves to have the greatest benefits on cognition and well-being. It will include 12 blocks of 30 seconds of work, performing as many repetitions as possible, followed by 15 seconds of static rest. It will last last 9 minutes and will be conducted after a 2-hour lecture. During the active rest period, heart rate will be moni

Sponsors

Universitat Jaume I
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SCREENING
Masking
SINGLE (Investigator)

Masking description

The assignment to the different conditions will be carried out using a random number generation program stratifying by sex (i.e., the randomizer.org tool).

Intervention model description

The study will be carried out following a crossover design with comparisons between the subjects, in which the cognition and the affective dimensions will be analysed before and after each experimental condition (acute exercise vs. sedentary control).

Eligibility

Sex/Gender
ALL
Age
18 Years to 24 Years
Healthy volunteers
Yes

Inclusion criteria

* Not to be diagnosed with psychological and/or cognitive alterations or pathologies that may limit the understanding and following of the instructions provided by another person. * Not to suffer physical alterations that may limit the practice of physical activity. * To be between 18 and 24 years old.

Exclusion criteria

* To be diagnosed with psychological and/or cognitive alterations or pathologies that may limit the understanding and following of the instructions provided by another person. * To suffer physical alterations that may limit the practice of physical activity. * Not to be between 18 and 24 years old.

Design outcomes

Primary

MeasureTime frameDescription
Attention (cognition)10 minutes before and 10 minutes after the intervention protocolThe participants will take the d2-R test to measure their attention. The test shows different rows of randomly mixed letters from which the target symbol is a "d" with two dashes. The participants must select all the "d" with two dashes while ignoring all the other symbols.
Positive and negative affect (wellbeing)10 minutes before and 10 minutes after intervention protocolIn order to assess the positive and negative affect, the participants will take the Positive and Negative Affect Schedule (PANAS). It is a self-report measure that is made up of two mood scales, one measuring positive affect (the scores ranging from 10 to 50, with higher scores meaning better wellbeing) and the other measuring negative affect (the scores ranging from 10 to 50, with higher scores meaning worse wellbeing).

Countries

Spain

Contacts

PRINCIPAL_INVESTIGATORMaria Reyes Beltran Valls, PhD

Universitat Jaume I

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 8, 2026