Coronary Heart Disease
Conditions
Brief summary
The aim of this observational study is to compare the prognostic outcomes of various PCI strategies in elderly patients with complex coronary calcified lesions. The patients will be classified into two groups and assigned different PCI strategies, either stenting or stenting combined with pharmacologic balloon implantation. The investigators will assess the one-year prognosis for major adverse cardiovascular events in these patients.
Sponsors
Henan Institute of Cardiovascular Epidemiology
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥ 60 years; 2. Meet the indications for coronary intervention; 3. IVUS examination suggests severe calcified lesions (calcification angle \>270°) or OCT examination suggests severe calcified lesions (calcification angle \>180° and/or length \>5mm and/or thickness \>0.5mm); 4. The diameter of the target lesion vessel is greater than 2.75mm; 5. The total length of the lesion is more than 60mm and/or the number of lesions to be treated is ≥3 and/or the number of vessels to be treated is ≥2.
Exclusion criteria
1. inability to provide written informed consent; 2. inability to administer antiplatelet agents and anticoagulant therapy; 3. the subject is participating in other unfinished clinical trials; 4. life expectancy \<1 year; 5. non-in situ vascular lesions; 6. patients with haemodynamic instability; 7. Previous stroke within 6 months. 8. left main stem lesions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MACEs | 12 months | A Composite Event Including Cardiac Death, Myocardial Infarction, Stroke, and Target Vessel Revascularization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac Death | 12 months | Cardiac Death |
| Myocardial Infarction | 12 months | Myocardial Infarction |
| Target Vessel Revascularization | 12 months | Target Vessel Revascularization |
| Stroke | 12 months | Stroke |
| BRCA 2,3-5 | 12 months | BRCA 2,3-5 |
Countries
China
Contacts
Primary ContactQuan Guo
Outcome results
None listed