Preterm Labor, Respiratory Distress Syndrome
Conditions
Keywords
Preterm Labor, Respiratory Distress Syndrome, Fetal Lung Elastography, Elastography
Brief summary
The aim of this study was to compare fetal lung elastography (FAE) values between groups with and without Respiratory Distress Syndrome (RDS) in preterm neonates and to evaluate the potential of FAE to predict the risk of developing RDS.
Detailed description
The evaluate the potential of fetal lung elastography as a non-invasive method to predict and treatment respiratory complications in preterm neonates. FAE is an imaging method that measures the elasticity properties of fetal lung tissue using ultrasound technology. This method can be helpful in providing information about the development and respiratory function of the fetal lungs. The advantages of FAE are: It is a non-invasive method: FAE is performed using ultrasound technology and has no known maternal or fetal harm. It stands as a potentially safe method compared to current invasive tests. It is cost-effective and easy to perform: FAE is a procedure performed using existing ultrasound equipment at no separate cost. Therefore, it can be easily implemented and repeated in clinical settings. Fast results: FAE provides fast results by acquiring images in real time. This indicates that FAE can be a valuable diagnostic tool in emergency situations or when rapid decision-making is required. A potential predictive tool: The results of this study may indicate that FAE values are a potential tool for predicting the risk of developing RDS. This could be an important step to develop early diagnosis and treatment strategies to improve the respiratory health of preterm newborns.
Interventions
DIAGNOSTIC_TESTfetal lung elastography measurement
Elastography measurements are planned to be performed as in the studies "Feasibility of two-dimensional ultrasound shear wave elastography of human fetal lungs and liver: A pilot study" and "Feasibility of 2-D ultrasound shear wave elastography of fetal lungs in case of threatened preterm labour: a study protocol" in the literature examples section of the file.
Sponsors
Ankara Etlik City Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
24 Weeks to 34 Weeks
Healthy volunteers
Yes
Inclusion criteria
* 18-45 years old * Single pregnant women who were followed up with a diagnosis of preterm labor between 24-33 weeks and who volunteered and consented to the study * Measured at least 24 hours after antenatal corticosteroid and delivered within a maximum of 72 hours after measurement
Exclusion criteria
* Multiple pregnancies * Amniotic fluid pathologies * Fetal lung and liver diseases * Fetal genetic and structural anomalies * Signs and diagnoses of systemic maternal diseases * Advanced maternal obesity preventing measurement * Patients hospitalized with a diagnosis of preterm labor and discharged before delivery * Presence of comorbid diseases of pregnancy (GDM, hypertensive diseases of pregnancy, PPROM, chorioamnionitis etc.) * Pregnant women over 45 years of age, systemic conditions (history of chronic, mental, physical illness, severe renal, hepatic, gastrointestinal acute/chronic inflammatory disease, hyperthyroidism, hypothyroidism, hypertension, type 1/2 DM, history of malignancy, smoking, alcohol use)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fetal Lung Elastography Measurement | Prenatal (24-34 gestational weeks, before 72 hours to delivery) | Measurement of prenatal ultrasonographic shear wave elastographic values(kPa) of the fetus in cases of preterm labor |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORAhmet Kurt, 1
Ankara Etlik City Hospital
Outcome results
None listed