Allergy, Allergy Drug, Allergy;Food, Allergy Pollen
Conditions
Brief summary
The purpose of this study is to develop a microarray-based diagnostic test system for the determination of allergen specific IgE in human blood serum.
Detailed description
The purpose of this study is to develop a microarray-based diagnostic test system for the determination of allergen specific IgE in human blood serum samples and to assess the sensitivity and specificity of the developed system.
Interventions
DIAGNOSTIC_TESTRoutine allergy tests
Prick test, specific IgE detection
DIAGNOSTIC_TESTNewly developed microarray-based diagnostic test system
Newly developed microarray-based diagnostic test system for the detection of the specific IgE
Sponsors
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Group of adult participants with IgE-dependent allergic reactions. Routine blood serum IgE levels will be compared with the newly developed microarray-based diagnostic test system.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Type I allergy (food, drug, pollen) * The patient can read, understand, follow the examination procedures and complete, if necessary, the required documentation * Written informed consent
Exclusion criteria
* Acute or chronic diseases in the stage of decompensation (except allergy) * Chronic infectious diseases: HIV, viral hepatitis B, C, tuberculosis * Patients who are pregnant, breastfeeding * Chronic and protracted mental disorders, all diseases with the presence of the syndrome of dependence on alcohol, drugs and psychoactive substances, any other condition that makes the patient unable to understand the nature, extent and possible consequences of the study or, in the opinion of the researcher, prevents the patient from observing and performing protocol * Patients are unable or unwilling to give written informed consent and / or follow research procedures * Any other medical condition that, in the opinion of the investigator, may be associated with an increased risk to the patient or may affect the outcome or evaluation of the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum IgE levels of the specific pollen allergens | 1 month | Serum IgE levels of the specific pollen allergens will be sudied |
Countries
Belarus
Contacts
Primary ContactAndrei Hancharou, Dr
Outcome results
None listed