HFrEF - Heart Failure With Reduced Ejection Fraction
Conditions
Brief summary
OPTIMAL-HF is a pragmatic, cluster randomized, single-blind intervention trial that will be conducted at an outpatient clinic in Argentina. The trial will assess the effectiveness of an individualized-based alert system compared to usual care in improving GDMT optimization at 90 days in patients with HFrEF.
Interventions
OTHEREMR alert
EMR alert for medication optimization
Sponsors
Instituto Cardiovascular de Buenos Aires
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients Inclusion Criteria: * Eligible patients will include those with an EF ≤ 40% on their most recent echocardiogram, age \> 18, and an outpatient cardiology encounter during the study period. * Age 18 or over
Exclusion criteria
* under optimal medical treatment * palliative care, or undergoing hemodialysis will be excluded Cardiologist Inclusion criteria: Cardiologists from an outpatient clinic at a cardiovascular center in Buenos Aires will be selected for potential participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary efficacy endpoint will be the GDMT optimize score in HfrEF patients 90 days after randomization. | 90 days |
Contacts
Primary ContactLucrecia Burgos, MD
Outcome results
None listed