Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs

Clinical Comparison of Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06165458

Enrollment

Registered

2023-12-11

Start date

2021-01-12

Completion date

2022-02-15

Last updated

2023-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleaching Sensitivity, Color

Brief summary

This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and tooth sensitivity.

Interventions

OTHER6% hydrogen peroxide gel + violet LED

Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by violet LED

OTHER6% hydrogen peroxide gel + blue LED

Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by blue LED

OTHER35% hydrogen peroxide gel + violet LED

Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by violet LED

OTHER35% hydrogen peroxide gel + blue LED

Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by blue LED

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

OTHER

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* at age 18 or older, with good general and oral health; * possessing all six natural and healthy upper anterior teeth with a color shade of A2 or darker, determined by comparison with the Vita Classic scale;

Exclusion criteria

* pregnant and breastfeeding women; * individuals with internal tooth discoloration (tetracycline stains, fluorosis or hypoplasias); * smokers, or those with veneers or restorations on the teeth in questions were excluded; * gingival recession; * dentin exposure; * periodontal disease.

Design outcomes

Primary

Measure	Time frame	Description
Color	Color assessment was carried out before bleaching, 1 week after bleaching and 3 months after bleaching	A operator measured the color of the six upper anterior teeth using a digital spectrophotometer (VITA Easyshade V, Wilcos, Petrópolis, RJ, Brazil).
Bleaching Sensitivity	Assessments were carried out three times: before bleaching, immediately after bleaching, and 24 hours after bleaching.	The degree of tooth sensitivity of patients was recorded using a visual analogue scale (VAS) from 0 to 10, where 0 represents no tooth sensitivity and 10 represents the greatest tooth sensitivity ever felt by the patient.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026