The Comparison Between Computed Tomography and Colonoscope in Detecting Colorectal Tumors in Patients With FIT+

The Comparison of Diagnostic Yield Between Routine Computed Tomography and Colonoscope in Detecting Colorectal Tumors in Patients Who at Risk of Colorectal Cancer

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06165328

Acronym

CTOCOCREC

Enrollment

241

Registered

2023-12-11

Start date

2024-01-01

Completion date

2024-12-31

Last updated

2024-02-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients at Risk of Colorectal Cancer

Keywords

colorectal tumor, colorectal cancer, CT scan, colonoscopy

Brief summary

Colonoscopy is the mainstay modality of choice in colorectal cancer screening worldwide. However, the rate of colonoscopy for colorectal cancer screening is very low (approximately 5-10%) because of the limited local medical resources (such as endoscopists and regional endoscope). This observational diagnostic test study aims to compare the diagnostic yield of routine computed tomography and colonoscopy in detecting colorectal tumors in patients at risk of colorectal cancer (aged more than 50 years and FIT+). The main question\[s\] it aims to answer are: 1. To compare the diagnostic yield between the routine computed tomography and colonoscopy. 2. To compare the procedure-related adverse events between the routine computed tomography and colonoscopy.

Detailed description

All enrolled patients underwent routine CT scans of whole abdomen, then subsequently under went a colonoscopy on the next day

Interventions

DIAGNOSTIC_TESTCT and colonoscopy

All patients were admitted and worked up as inpatient cases. A blood test was obtained and a CT whole abdomen was performed for all patients in the evening. On the next day, all patients were prescribed for bowel preparation in the morning, then subsequently underwent colonoscopy in the afternoon.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Fit test + 2. Normal platelet count and normal result of PT, PTT

Exclusion criteria

1. pregnancy or lactation 2. uncontrolled Diabetes Mellitus, hypertension, asthma, congestive heart failure 3. recent coronary artery disease within 3 months 4. eGFR lesser than 30 mL/min/1.73m2 5. hemophilia or uncontrolled or uncorrected coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic yield in diagnosis colorectal tumor	2 weeks	Sensitivity, specitivity, accuracy

Secondary

Measure	Time frame	Description
Procedure-related adverse events	2 weeks	Procedure-related adverse events such as, contrast induced nephropathy, contrast allergy, colonoscope-related perforation, post polypectomy bleeding

Countries

Thailand

Contacts

Primary ContactArunchai Chang, MD

busmdcu58@gmail.com+66650979414

Backup ContactAraya Kaimook, MD

araya@cpird.in.th+66815424454

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026