Neuro-Degenerative Disease
Conditions
Brief summary
The aim of the study is to obtain information on cerebral glucose metabolism measured with the 18F-FDG PET technique in normal subjects without current or previous neurological or psychiatric pathologies in order to use the data obtained for voxel-based statistical analyzes for comparison with individual subjects ( patients with disease neurological or psychiatric) which will be evaluated with the same method to improve the specificity and diagnostic sensitivity of the FDG PET exam. The objective is to obtain a functional measure of brain glucose metabolism in every normal subject because this is a functional measure of brain activity. The subjects will represent different decades of age to have a wider range of comparison with patients.
Interventions
DIAGNOSTIC_TESTDiagnostic accuracy
The aim is to obtain a regional measure of brain glucose metabolism in each normal subject because this is a functional measure of brain activity.
Sponsors
IRCCS San Raffaele
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* absence of neurological and psychiatric pathologies, negative pregnancy test.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Study of glucose metabolism with 18 F FDG PET | 1 year | Study of glucose metabolism with 18 F FDG PET in normal subjects without current or previous neurological or psychiatric pathologies in order to use the data obtained for statistical analyzes for comparison with individual subjects (patients with neurological or psychiatric) which will be evaluated with the same method to improve the diagnostic sensitivity of the FDG PET exam. |
Outcome results
None listed