Antenatal Corticosteroid, Perinatal Problems, Preterm Pregnancy
Conditions
Keywords
Antenatal corticosteroids, Late preterm pregnancy, Late perinatal outcomes
Brief summary
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the literature in this sense.
Detailed description
This study is a single-center prospective case-control study investigating the effect of antenatal corticosteroids administered in the late preterm period on early and late perinatal outcomes. 459 patients who gave birth between 34-37 weeks between June 1,2021 to October 1,2022 in the Obstetrics and Gynecology Clinic of the University of Health Sciences were included. Patient were divided into two groups antenatal corticosteroid administration (n:231) and non-administration (n:228). Postpartum early and late perinatal outcomes were compared between these two groups.
Interventions
OTHERparticipants receiving Corticosteroid
Pregnant women using antenatal corticosteroids for any reason before 34 weeks
Sponsors
Sanliurfa Mehmet Akif Inan Education and Research Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* All pregnant women who had normal vaginal delivery, cesarean section or operative delivery between 34-37 weeks * Singleton pregnancies resulting in a live birth
Exclusion criteria
* Twin pregnancies * All births before 34 weeks or after 37 weeks * Pregnant women with intrauterine ex fetus * Fetuses with major congenital and chromosomal abnormalities * Pregnant women who administrated antenatal corticosteroids for any reason before 34 weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The results of antenatal corticosteroid effects | 16 months | intramuscular 3 mg betamethasone (dekort 8mg/2 ml) corticosteroid injection in perinatal period |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Other consequences of antenatal corticosteroid effects in late term pregnant women | 16 months | Other consequences of antenatal corticosteroid administered in late preterm pregnant women in the neonatal period are the need for neonatal intensive care due to reasons other than respiratory distress, respiratory complications such as pneumonia, other complications such as sepsis, perinatal death, chronic lung disease (even after 28 days of birth, oxygen need) long-term outcomes in postnatal infants ( third month, sixth month, twelfth month, emotional and emotional consequences in the family, and maternal side effects. |
Countries
Turkey (Türkiye)
Outcome results
None listed