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Evaluation of Fatigue Severity, Mood, and Quality of Life in Post-Polio Syndrome

Evaluation of Fatigue Severity, Mood, and Quality of Life in Post-Polio Syndrome: A Controlled Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06162104
Enrollment
40
Registered
2023-12-08
Start date
2023-12-01
Completion date
2023-12-19
Last updated
2024-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue, Polio, Polio and Post-polio Syndrome

Keywords

Poliomyelitis, Fatigue, Postpoliomyelitis Syndrome

Brief summary

The aim of this study is to investigate the differences in the severity of fatigue, impact on quality of life, and mood between individuals with post-polio syndrome and healthy volunteer groups. Additionally, the interrelationships of these parameters within the post-polio syndrome patient group will be examined. The goal is to raise awareness during the follow-up process for individuals with post-polio syndrome by questioning fatigue and mood symptoms, and to facilitate the implementation of necessary precautions.

Detailed description

Our research is designed as a case-control study. 20 patients diagnosed with post-polio syndrome who present to the Istanbul Physical Medicine and Rehabilitation Training and Research Hospital clinics and 20 healthy volunteers will be included in the study. The sociodemographic data of patients and volunteers, such as age, gender, height, weight, body mass index, education level, and occupation, will be recorded. The age at which polio was contracted, the time elapsed since polio, and any accompanying illnesses will be documented. Additionally, if patients experience new symptoms such as pain, weakness, or fatigue, the severity of these symptoms will be assessed using the Visual Analog Scale. The frequency of falls and the presence of fractures caused by falls, ambulation method, and devices used will be noted. Muscle weakness in the extremities will be identified by applying the Manual Muscle Test through physical examination. Subsequently, the patient's current symptoms related to depression and anxiety will be evaluated using the Hospital Anxiety and Depression Scale (HADS), fatigue level will be assessed using the Fatigue Severity Scale (FSS), and quality of life will be evaluated using the Short Form-36 (SF-36).

Interventions

OTHERNo intervention

No intervention

Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Individuals aged between 18 and 60 with post-polio syndrome. * Healthy volunteers aged between 18 and 60

Exclusion criteria

* fibromyalgia, * chronic fatigue syndrome, * presence of chronic decompensated cardiac, renal, and hepatic insufficiency, * known psychiatric disorders, * rheumatological diseases, * presence of other known neurological diseases, * use of medications aimed at improving physical performance or alleviating fatigue.

Design outcomes

Primary

MeasureTime frameDescription
Fatigue Severity Scale0 dayThis scale consists of 9 items assessing the severity of fatigue and its impact on individuals. Each item is scored on a scale ranging from 0 to 7.

Secondary

MeasureTime frameDescription
Short Form-360 dayThis form comprises 36 items that inquire about the quality of life. Lower scores indicate a poorer condition.
Hospital Anxiety and Depression Scale0 dayThis scale is a 14-item assessment method, consisting of 7 questions each, designed to inquire about symptoms related to anxiety and depression in patients. As the score increases, the level of anxiety and depression worsens.
Visual Analogue Scale0 dayThe Visual Analog Scale is a simple measurement tool consisting of a line with endpoints representing extreme points of a characteristic, such as No Pain to Worst Pain Imaginable. Respondents mark a point on the line to indicate their perception or experience of the given characteristic.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026