Apnea, Hypercapnia, Hypoxia, Pain
Conditions
Brief summary
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.
Interventions
OTHERVoluntary apnoea
Walking apneas at low lung volume
Sponsors
Centro Universitario La Salle
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
\- Asymptomatic subjects aged between 18 and 64 years.
Exclusion criteria
* Cardiovascular, respiratory, metabolic, neurological or osteomuscular signs or pathologies. * History of epilepsy. * Pregnant * Pharmacological treatment. * Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 4 weeks.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain pressure threshold (PPT) on thumb, anterior tibial and spinous process of C7 | before and after intervention (up 30 minutes) | PPT is tested on the dorsal base of the distal phalanx of the thumb on the dominant side and on the muscle belly of the tibialis anterior on the dominant side. The region to be pressed is marked with a pen. The patient is instructed to report with the first appearance of the sensation of discomfort. An ascending ramp of 0.5 kg/cm/s is applied, at the rhythm of a metronome. The measurement is started on the thumb, and alternated with tibia and C7 until 3 measurements of each region are obtained, enough time to give 30 seconds of rest between measurements in the same region. This protocol has demonstrated high inter-observer reliability measuring healthy subjects (ICC = 0.91). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pittsburg Sleep Quality Index (PSQI) | before intervention (up 5 minutes) | 9-item questionnaire on sleep quality in the past month. The scale has a range of scores from 0 to 21. The lower the score, the more favorable for the patient's health. |
| Global Physical Activity Questionnaire (GPAQ) | before intervention (up 5 minutes) | 6-item questionnaire on the level of physical activity at work, for commuting and in leisure time. A higher score means higher weekly physical activity. |
| Heart rate | during intervention (up 6 minutes) | Heart rate will be measured during the procedure by finger pulse oximetry. |
| Perceived Stress Scale (PSS) | before intervention (up 5 minutes) | 14-item questionnaire about their thoughts and feelings in the last month. The scale has a range of scores from 0 to 56. The lower the score, the more favorable for the patient's health. |
| Blood pressure | before, during and after intervention (up 10 minutes) | Systolic and diastolic blood pressure will be measured before, during and immediately after the procedure using a digital wrist sphygmomanometer. |
| Rate of perceived exertion (RPE) | immediately after intervention (up 10 seconds) | RPE Borg CR-10 is used to measure how hard your body works during physical activity. It runs from 0 - 10, using numbers to rate how much effort an activity takes. |
| Oxygen saturation | during intervention (up 6 minutes) | Oxygen saturation will be measured during the procedure by finger pulse oximetry. |
Countries
Spain
Outcome results
None listed