Hereditary Cancer
Conditions
Brief summary
To learn if educational videos can help participants be more informed about hereditary cancers (ones that run in the family).
Detailed description
Primary Objective Determine the impact of educational videos on: * Participant's hereditary cancer knowledge. * Participant's confidence to share hereditary cancer information with family members. Secondary Objective * Determine impact of educational videos on participant's confidence to undergo hereditary cancer screening. * Identify opportunities to tailor and improve the educational video's content, style, and understandability per participant preferences and feedback.
Interventions
BEHAVIORALInterview Study
All study participants will have the following demographic information collected from their medical records: * Sex (Male/Female/Other) * Date of birth * Preferred language (English/Spanish) * Health insurance status (for example: private insurance, HCHD "gold card") * Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) * Genetic testing result (gene with pathogenic/likely pathogenic variant) * Date of genetic testing result * Date of documented result disclosure.
BEHAVIORALSurvey Study
All study participants will have the following demographic information collected from their medical records: * Sex (Male/Female/Other) * Date of birth * Preferred language (English/Spanish) * Health insurance status (for example: private insurance, HCHD "gold card") * Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) * Genetic testing result (gene with pathogenic/likely pathogenic variant) * Date of genetic testing result * Date of documented result disclosure.
Sponsors
M.D. Anderson Cancer Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Participants of The Harris Health System Lyndon B. Johnson (LBJ) Hospital outpatient oncology clinics (i.e., Gynecologic Oncology, Medical Oncology). 2. 18 years of age or older. 3. Speaks and/or reads English or Spanish. 4. Has a pathogenic or likely pathogenic variant (mutation) in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM on germline genetic testing. 5. Has a documented genetic testing results disclosure encounter (i.e. telephone call, follow-up appointment).
Exclusion criteria
1. No longer receives outpatient care at LBJ Hospital at time of recruitment. 2. Has only a variant of uncertain significance in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM. 3. Has only a pathogenic or likely pathogenic variant in gene other than BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM. 4. Is unwilling, unable, or requires a legally authorized representative to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hereditary Cancer Multidimensional Measure of Informed Choice Questionnaires | through study completion; an average of 1 year | Hereditary Cancer Multidimensional Measure of Informed Choice (MMIC) Knowledge Score scale: (1-8) true or false |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORJose Rauh-Hain, MD
M.D. Anderson Cancer Center
Outcome results
None listed