Outcome Analysis of Endoscopic Resection of Pituitary Adenomas

Analysis of Operative Outcomes Following Endoscopic Resection of Pituitary Adenomas

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06156020

Enrollment

500

Registered

2023-12-05

Start date

2020-01-01

Completion date

2025-12-31

Last updated

2024-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary Adenoma

Keywords

pituitary adenoma

Brief summary

The goal of this prospective study is to learn about the operative outcomes in patients with pituitary adenoma who receive endoscopic resection. The main question it aims to answer is: • What are the outcomes of patient following endoscopic resection? including visual, hormonal, survival, and functional outcomes. Participants' data including clinical history, laboratory data, radiographic images, intraoperative videos will be evaluated and analyzed.

Interventions

PROCEDUREEndoscopic endonasal surgery

Endoscopic endonasal transsphenoidal approach for resection of pituitary adenomas

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Adult patient * Pathological diagnosis of pituitary adenoma * Underwent endoscopic endonasal resection

Exclusion criteria

* Age \< 18 or \> 80 years * Non-pituitary adenoma pathologies * Underwent non-endoscopic surgery

Design outcomes

Primary

Measure	Time frame	Description
Cortisol level	6 months	Postoperative serum cortisol level will be measured and compared to preoperative levels.
Thyroid hormone level	6 months	Postoperative serum TSH and free T4 level will be measured and compared to preoperative levels.
Visual field	6 months	The postoperative visual field will be assessed with standard visual perimetry and compared with preoperative measurements.
Diabetes insipidus	6 months	Postoperatively, the patient's urine output and urine specific gravity will be measured to determine if the patient had diabetes insipidus. If the patient had diabetes insipidus, the duration of the diabetes insipidus will be recorded.
Prolactin level	6 months	Postoperative serum prolactin level will be measured and compared to preoperative levels.
IGF-1 level	6 months	Postoperative serum IGF-1 level will be measured and compared to preoperative levels.

Countries

Taiwan

Contacts

Primary ContactJung-Shun Lee, MD

nslee1218@gmail.com+886-6-2353535

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026