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Upper Gastrointestinal Perforations: a Nationwide Registry-based Study

Risk Factors for and Survival After Oesophageal, Gastric and Small Intestinal Perforations: a National Observational Registry-based Cohort Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06154603
Enrollment
2000
Registered
2023-12-04
Start date
2025-08-31
Completion date
2026-08-31
Last updated
2024-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Abdomen

Keywords

Clinical outcomes, General surgery, Upper gastrointestinal perforation

Brief summary

The primary aim of this project is to increase the knowledge about how perforations in the esophagus, stomach and small intestine are treated on a national level. Furthermore, secondary aims include assessment of how different treatment options and type of treating facilities relate to patient survival. This will be done by studying information about all adult patients with an upper GI perforation treated in Sweden during 2005-2023.

Interventions

PROCEDURESurgical treatment type

This observational design will study the clinical outcome for each type of upper gastrointestinal perforation in relation to surgical or non-surgery treatment and in relation to treatment centre.

Sponsors

Region Stockholm
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* age of at least 18 years * perforation in either oesophagus, stomach or small intestine * treatment carried out in Sweden * diagnosis set between January 2005 and August 2023

Exclusion criteria

* children

Design outcomes

Primary

MeasureTime frameDescription
MortalityOne year after diagnosisMortality up to one year after diagnosis

Countries

Sweden

Contacts

Primary ContactRebecka Ahl Hulme, MD, PhD
rebecka.ahl-hulme@regionstockholm.se0046812373212

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026