Cognitive Impairment
Conditions
Keywords
Cognitive Impairment, Outpatient Neurologic Service, Population Distribution
Brief summary
Memory in Neurology project (PAMNEU) aims to map the distribution and severity of cognitive impairment in patients of outpatient neurologic offices across the geographical area of the Czech Republic. 1000 patients in 50 neurologic offices will undergo cognitive tests (ALBA and PICNIR) and psychometric scales (FAQ-CZ and GDS-CZ) to asses their functional state and depressive symptoms. The trial's primary goal is to assess the distribution of cognitive impairment among diagnostic groups in neurologic care according to the ICD-10. Additionally, the feasibility of ALBA and PICNIR methods to uncover previously undiagnosed cognitive impairments will be evaluated.
Interventions
None listed
Sponsors
Charles University, Czech Republic
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Dispensarization of at least six months in an outpatient neurologic office with an ICD-10 diagnosis * Age\>=50 * Permanent residency in the geographical area of the Czech Republic
Exclusion criteria
* Diagnosis of mental retardation (F70-F79) according to ICD-10 * Refusal to sign the informed consent and consent with GDPR * Uncorrected visual impairment * Uncorrected auditory impairment * Impairment of hand movement preventing the patient from filling in the questionnaires. * Inability to participate in the project
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline ALBA | Established on Day 0 as a single assessment. | Amnesia Light and Brief Assessment (ALBA) test is an innovative method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-12 (a lower value denotes a more severe cognitive impairment). |
| Baseline PICNIR | Established on Day 0 as a single assessment. | Picture Naming and Immediate Recall test (PICNIR) is an innovative test method to assess cognitive functions quickly. The cognitive performance is scaled as an overall score between 0-20 (a lower value denotes a more severe cognitive impairment). |
| Statistical analysis of ALBA results | The final statistical analysis will be performed through study completion, an average of 6 months. | Statistical analysis of ALBA results compared to groups determined by ICD-10 diagnosis and demographical data. |
| Statistical analysis of PICNIR results | The final statistical analysis will be performed through study completion, an average of 6 months. | Statistical analysis of PICNIR results compared to groups determined by ICD-10 diagnosis and demographical data. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Baseline FAQ-CZ | Established as a baseline on Day 0. | Functional Activities Questionnaire - Czech version (FAQ-CZ) is a standardized questionnaire administered to assess a patient´s functional state regarding daily activities. Ten items of daily functioning are scaled between 0-3 (a higher value denotes a higher dependency) to reach the overall score between 0-30 (a higher value denotes a higher dependency). This version of the scale will be used for participants´ self-evaluation. |
| Baseline GDS-CZ | Established as a baseline on Day 0. | The Geriatric Depression Scale - Czech version (GDS-CZ) is a standardized questionnaire administered to assess depressive symptoms, particularly in the elderly population. Fifteen items are scaled between 0-1 to reach the overall score between 0-15 (a higher value denotes a higher level of depressive symptoms). |
Countries
Czechia
Outcome results
None listed