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Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06151301
Enrollment
60
Registered
2023-11-30
Start date
2023-12-01
Completion date
2024-12-01
Last updated
2023-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Hydrocarbon Toxicity

Brief summary

Hydrocarbons are a primary energy source in modern society. They are present in many common household and occupational products, including motor fuels, paint thinners, cleaning agents, lotions, and industrial solvents. Unfortunately, these products are also used as agents of abuse and typically inhaled . They are derived mainly from petroleum (kerosene, gas, naphtha) or wood (turpentine, pine oil). They can be found in liquid, gas, or solid form depending on their properties. All hydrocarbons can be toxic, but aromatic (ring-shaped) and halogenated hydrocarbons typically have more severe toxicity . Toxicity occurs in various ways including through inhalation, ingestion, aspiration, and dermal exposure. Frequently, these exposures occur during attempted recreational use of the substances and sometimes for self-injurious behavior

Interventions

DIAGNOSTIC_TESTserum procalcitonin

predicting the severity of intoxication

DIAGNOSTIC_TESTC-reactive protein

predicting the severity of intoxication

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Patients of both sexes admitted to the Poison control center, Ain Shams university hospitals with acute hydrocarbon toxicity during the duration from December 2023 till December 2024 with a maximum number of 60 cases within 24 hours of intoxication.

Exclusion criteria

Patients with these criteria will be excluded: * Cases \> 24 hours of intoxication. * Cases with occupational exposure to hydrocarbons. * Pregnant females. * Any cases received any treatment before arrival to the PCC. * Cases suffering from cardiac, respiratory, renal, hepatic or haematological disorders. * Cases presenting with fever. * Cases with other causes that can increase levels of CRP & pro-calcitonin as bacterial infection, recent major trauma, major burn ,septic shock and medullary thyroid cancer.

Design outcomes

Primary

MeasureTime frameDescription
Serum procalcitonin level1 yearmeasuring the level of serum procalcitonin (reference range 0-0.05µg/L)

Countries

Egypt

Contacts

Primary ContactMera G Khalil, assistant lecutrer
Mera_Sadek@med.sohag.edu.eg01229185948
Backup ContactMaha A Helal, professor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026