Acute Hydrocarbon Toxicity
Conditions
Brief summary
Hydrocarbons are a primary energy source in modern society. They are present in many common household and occupational products, including motor fuels, paint thinners, cleaning agents, lotions, and industrial solvents. Unfortunately, these products are also used as agents of abuse and typically inhaled . They are derived mainly from petroleum (kerosene, gas, naphtha) or wood (turpentine, pine oil). They can be found in liquid, gas, or solid form depending on their properties. All hydrocarbons can be toxic, but aromatic (ring-shaped) and halogenated hydrocarbons typically have more severe toxicity . Toxicity occurs in various ways including through inhalation, ingestion, aspiration, and dermal exposure. Frequently, these exposures occur during attempted recreational use of the substances and sometimes for self-injurious behavior
Interventions
predicting the severity of intoxication
predicting the severity of intoxication
Sponsors
Study design
Eligibility
Inclusion criteria
Patients of both sexes admitted to the Poison control center, Ain Shams university hospitals with acute hydrocarbon toxicity during the duration from December 2023 till December 2024 with a maximum number of 60 cases within 24 hours of intoxication.
Exclusion criteria
Patients with these criteria will be excluded: * Cases \> 24 hours of intoxication. * Cases with occupational exposure to hydrocarbons. * Pregnant females. * Any cases received any treatment before arrival to the PCC. * Cases suffering from cardiac, respiratory, renal, hepatic or haematological disorders. * Cases presenting with fever. * Cases with other causes that can increase levels of CRP & pro-calcitonin as bacterial infection, recent major trauma, major burn ,septic shock and medullary thyroid cancer.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum procalcitonin level | 1 year | measuring the level of serum procalcitonin (reference range 0-0.05µg/L) |
Countries
Egypt