Alopecia Areata
Conditions
Keywords
excimer light
Brief summary
This study aimed to evaluate the efficacy and safety of the 308-nm excimer lamp in resistant AA treated with topical minoxidil .
Detailed description
Alopecia areata (AA) is a chronic, nonscarring, T-cell mediated autoimmune disease, presenting with localized or diffuse hair fall in hair-bearing areas. Approximately 1.7% of the population experience an episode of AA during their lifetime. Both sexes are equally affected, and most new cases are recorded below the age of 30 years . Excimer laser using high-dose monochromatic UV radiation can trigger apoptosis and induce immunological suppression through altering cytokine production such as IL-4, IL-10, prostaglandin E2, platelet-activating factor, and cis-urocanic acid. Benefits have only been seen with localized patches of AA, and regrowth of hair occurs only in treated areas .
Interventions
DEVICEexcimer light
Excimer laser using high-dose monochromatic UV radiation
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Inclusion criteria
* ● Having multiple patches of AA. * Duration of alopecia \>1 year * No topical or systemic treatment for the last 4 months * Agreement to regular visits for treatment and follow-up.
Exclusion criteria
* ● A single form of AA. * Alopecia for \<1 year. * Being on other modalities of treatment. * Treatment within the last 4 months. * Photosensitive disorders. * Pregnancy or breastfeeding.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| alopecia areata with ecimer light | 3 months | evulate patients monthly during treatment with excimer light and minoxidil gel for three months With 20 patients who should completely recovered from alopecia areata. |
Contacts
Primary Contacthagar maher, master
Outcome results
None listed