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Virtual Reality at End-of-life

The Impact of a Novel Virtual Reality Protocol on Presence and Symptom Severity at the End-of-life.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06149429
Enrollment
9
Registered
2023-11-29
Start date
2023-10-23
Completion date
2024-07-15
Last updated
2024-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Appetite Loss, Depression, Dyspnea, End of Life, Fatigue, Nausea, Pain, Well-Being, Psychological

Keywords

Hospice, Serious Illness, Virtual reality, End-of-life

Brief summary

The purpose of this research is to determine the effect that repeated, personalized virtual reality experiences have on symptom severity, comparing self-reported symptom severity both pre and post each session, and overtime across sessions. Researchers will also determine if this intervention results in a high rating of presence in VR, and if presence is related to the magnitude of the change in symptoms.

Detailed description

The purpose of this research is to determine the effect that repeated, personalized virtual reality experiences have on symptom severity, comparing self-reported symptom severity both pre and post each session, and overtime across sessions. The researchers will also determine if this intervention results in a high rating of presence in VR, and if presence is related to the magnitude of the change in symptoms. H1: Symptom severity will decrease from pre-intervention to post-intervention. H2: The change in symptom severity will be greater in session two than it was in session one. H3: Presence score will be higher in session two than session one. To recruit 30-40 participants, the researchers will have the clinical team working to help the research team identify eligible participants from existing caseloads. Researchers will include all hospice eligible patients, this includes people who are enrolled in hospice care but also a subset of those who are enrolled in palliative care who qualify for hospice but have refused to or haven't yet transitioned to hospice care. The site serves about 670 (as of May 2023) patients a month. Therefore, it is the researcher's intent to recruit about 3 patents per month, or a total of 30-40 patients (about 5% of the monthly population) over the course of one year. The intervention that participants will be experiencing is personalized virtual reality experiences. The content of this experience will be determined at the initial visit during which the participant will complete a preference questionnaire which identifies the location they want to go to. These experiences will be filmed on the insta360 One R camera by the research coordinator. Each experience will be approximately 20 minutes. To view the videos participants will wear the Oculus Quest 2 virtual reality headset.

Interventions

BEHAVIORALPersonalized virtual reality experience

The intervention that participants will be experiencing is personalized virtual reality experiences. The content of this experience will be determined at the initial visit during which the participant will complete a preference questionnaire which identifies the location they want to go to. These experiences will be filmed on the insta360 One R camera by the research coordinator. Each experience will be approximately 20 minutes. To view the videos participants will wear the Oculus Quest 2 virtual reality headset.

Sponsors

State University of New York - Upstate Medical University
CollaboratorOTHER
State University of New York at Buffalo
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

Single group open pilot, pre- post-intervention study

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Healthy volunteers are not applicable to this study as they study focuses on pain and symptom management at end-of-life through the virtual reality experience. Inclusion Criteria: * Patients who are hospice care eligible as defined by the Medicare Hospice benefit and receive hospice or palliative care from Hospice and Palliative Care Buffalo.

Exclusion criteria

* Their Palliative Performance Score (PPS) is below 30. * They are not cognitively intact (display symptoms of delirium or senility, or have a cognitive diagnosis such as Alzheimer's or Dementia) as measured by the Confusion Assessment Method (CAM) (Inouye et al., 1990) * They have hearing, vision, or speech impairments that are uncorrected. * They have current symptoms of or a history of dizziness, nausea, headaches, migraines, seizures, or motion sickness. * They do not speak English. * They are not 18 years old.

Design outcomes

Primary

MeasureTime frameDescription
Edmonton Symptom Assessment System - Revised (ESAS)Two weeksEnd-of-life symptom assessment

Secondary

MeasureTime frameDescription
igroup presence questionnaire (IPQ)Two weeksPresence during virtual reality experience

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026