Neoplasms
Conditions
Brief summary
Advanced Cancer patients hospitalized in a Cancer center inpatient unit have a dismal prognosis. Palliative Care interventions have shown multiple benefit for those patients, regarding quality of life, symptom management, illness understanding and aggressiveness of care criteria. Although Advance Care planning (ACP) is part of usual Palliative Care, specific interventions dedicated to ACP are understudied. This study aims at showing that a simple and systematic Advance Care Planning intervention is likely to clarify the understanding of the goals of care by patients, to help with ACP documentation and and potentially to modify the trajectory of illness for patients during and after hospitalization.
Detailed description
PREVOIR is a randomized, single-center, two-arm trial: patients from experimental arm will benefit from a systematic interview on the care plan whereas patients from control arm will received standard cares.
Interventions
Standardized interview based on The letter Project (Stanford Medicine) and Questions Prompt List
Sponsors
Institut de cancérologie Strasbourg Europe
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 years or older * Patients with a diagnosis of advanced or metastatic solid cancer * Patients hospitalized in a conventional oncology, radiotherapy or hematology department * Agreement obtained from the referring oncologist or senior doctor responsible for the patient during hospitalization * Patient hospitalized for less than 7 days * Patients who have not yet written advance directives * Signature of informed consent
Exclusion criteria
* Patients treated for hematologic malignancies * Presence of uncontrolled symptoms that do not allow an interview to be carried out * Patients with planned hospitalization for chemotherapy or biopsy or performance of a procedure * Patients \< 18 years old or patients ≥ 18 years old under supervision * Patients placed under judicial protection or guardianship * Decompensated neuropsychiatric disorders * Comprehension problems * Patients without social security * Allophone patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of patients who write advance directives of living at 3 months | At 3 months from randomization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Received anti-cancer treatment | up to 6 months | Prevalence of antineoplastic treatment received within the 3 months that precede death |
| Patients living trajectory | up to 6 months | Recording of patient site of death, if applicable |
| Percentage of patients who write advance directives of living at 1 month | At 1 month from randomization | — |
| Percentage of patients who write advance directives of living at 6 months | At 6 months from randomization | — |
| Overall survival | Up to 6 months | — |
Countries
France
Outcome results
None listed