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Great Occipital Nerve Block Using Different Approach

Comparison of Pain Relief and Block Success of Great Occipital Nerve Block Using Different Approach Method at C2 Level

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06149299
Enrollment
24
Registered
2023-11-28
Start date
2023-11-13
Completion date
2024-06-30
Last updated
2023-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Chronic

Brief summary

Great occipital nerve (GON) block is commonly applied for the pain management of occipital neuralgia, migraine, and cervicogenic headache. The GON orginates from the medial branch of the dorsal ramus of the C2 spinal nerve with variable contribution from the C3 dorsal ramus. After emerging from the suboccipital triangle, the nerve courses cephalad in an oblique trajectory between the semispinalis capitis (SC) and obliqus capitis inferior (OCI) muscles. This area was recognized as a potential location for GON injury. The nerve then passes through the trapezius muscle and courses medial to the occipital artery as it ascends to innervate the posterior scalp. Many practitioners perform GON injections using a conventional approach, relying solely on superficial bone-based anatomic landmarks to infiltrate local anesthetic and corticosteroid around the nerve at the level of the superior nuchal line. Some clinicians also use fluoroscopy to confirm the location of bony landmarks. The ambiguity of these injections poses a risk of anesthetizing adjacent structures or injecting into vessels, such as the occipital artery. Very limited research has been done to quantify the risk of these injections, but a complication rate of 5% to 10% has been reported, including headache, dizziness, blurred vision, and syncope. Ultrasound guidance is increasingly used to mitigate these risks and improve the efficacy of GON injections. Multiple studies have demonstrated successful ultrasound-guided GON blockade at the superior nuchal line and improvement in pain scores compared with nonguided injections. C2 level GON block using ultrasound targets interfascial plane between OCI and SC muscles. However, a pain physician who begins ultrasound guided injections migth feel very difficult targeting interfascial plane exactly. Since GON orginiates from deep space of suboccipital triangle, it is expected that injection within OCI muscle might have similar effect with the effect of injection into interfascial plane. We assume that if the local anesthetics is injected within OCI muscle, the effect of GON block will be generated by the diffusion of injected local anesthetics.

Interventions

Greater occipital nerve block using ultrasound guidance

Sponsors

Keimyung University Dongsan Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Cervicogenic headache * Migraine * Occipital neuralgia

Exclusion criteria

* bilateral headache * cervical spine surgery within 1 year before * loss of sensory sensation at the dermatome of GON innervation * anatomical defect at the region of procedure * coagulopathy * pregnancy or breast feeding * allergy to local anesthetics

Design outcomes

Primary

MeasureTime frameDescription
Numerical rating scaleBaseline, 30 minutes, 2 weeks, 4 weeks after the completion of GON blockNumerical rating scale after GON block
block successBaseline, 30 minutes after the completion of GON blockblock success after GON block

Secondary

MeasureTime frameDescription
Side effect after GON blockBaseline, 30 minutes after the completion of GON blockSide effect after GON block

Countries

South Korea

Contacts

Primary ContactJi H Hong
swon13@daum.net+821046794343

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026