Knee Osteoarthritis
Conditions
Brief summary
Osteoarthritis (OA) is the most prevalent form of arthritis. Its pathogenesis remains poorly understood. Though historically regarded as a disease of mechanical degeneration, it is now appreciated that inflammation plays an important role in OA pathogenesis (Krasnokutsky et al., 2017). The hallmark of OA is the degradation and loss of articular cartilage, although most tissues of the joint become affected, such as bone, synovium, ligaments, menisci (knee), labrum (hip), periarticular fat, and muscle (Englund, 2023).It is believed that there is a pathological link between hyperuricemia and OA Therefore, we conducted a cross-sectional study to evaluate an association between elevated SUA and radiographic OA of the knee) Bipan Shrestha, 2019 (.
Interventions
DIAGNOSTIC_TESTserum uric acid
to detect the relaton ship of serum uric acid with sevwrity of knee osteoarthritis
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adult patient (Age\>18 years) with a complaint of knee pain.
Exclusion criteria
* 1.Any patient with a history of trauma to the knee. 2 Any patient with knee complaints as a part of autoimmune connective tissue disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| percentage of serum uric acid | 6 months | detect the relationship of serum uric acid with severity of knee osteoarthritis |
Countries
Egypt
Contacts
Primary ContactAya M Saber, resident
Backup ContactAbdullah M Ahmed, assistant professor
Outcome results
None listed