Diabetes Mellitus, Prostatic Hyperplasia
Conditions
Brief summary
The study aims to compare the effect of two different classes of anti- diabetes medications on prostate volume and symptoms in elderly patients with diabetes mellitus
Detailed description
The study aims to compare the effect of two different classes of anti- diabetes medications on prostate volume and symptoms in elderly patients with diabetes mellitus The study compares sodium glucose cotransporter 2 inhibitors to Dipeptidyl peptidase 4 inhibitors in elderly patients with type 2 diabetes mellitus
Interventions
Questionnaire of 8 questions to be administered to all patients about prostate symptoms
DIAGNOSTIC_TESTAssessment of prostate volume
Measurements using ultrasound
Questionnaire to assess quality of sleep
DIAGNOSTIC_TESTGlycated hemoglobin
Measures control of diabetes
Sponsors
Kasr El Aini Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with diabetes and benign prostatic hyperplasia should be on monotherapy with either SGLT inhibitor or DDP4 inhibitors
Exclusion criteria
* unable to consent to the blood sampling or ultrasound Any other diabetes control measure other than SGLT inhibitors or DDP 4 inhibitors
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in prostate volume | one year | The delta change in prostate volume as measured by Ultrasound |
| Change in prostate symptoms | one year | As indicated by change in the International prostate score system |
Countries
Egypt
Outcome results
None listed