Age Problem, Colorectal Cancer
Conditions
Keywords
Colorectal caner, Age group, Family history, Symptomatic characteristics, Pathologic features
Brief summary
This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.
Detailed description
Colorectal cancer is one of the common and highly prevalent malignant tumors of the gastrointestinal system. Previous studies have found that there may be some differences in disease characteristics and prognosis of colorectal cancer patients at different ages, such as patients with early-onset colorectal cancer (age \<50 years) tend to have a worse prognosis than patients with late-onset colorectal cancer (age ≥50 years). However, existing studies on the characteristics of colorectal cancer patients at different ages are not well studied to answer the differences between these patients and develop targeted diagnostic and treatment strategies. Cross-sectional survey research, which uses survey research to collect data on a characteristic group over a certain period of time and statistically analyzes the data to obtain the characteristics of a certain disease or a certain treatment strategy, is a more mature approach that is particularly suitable for the questions that need to be answered in this study. Investigators found that no similar studies have been registered and conducted by searching the official websites of the China Clinical Research Registry and Clinical Trial, and there is a lack of research data on the Chinese population. Therefore, investigators believe there is an urgent need for a cross-sectional survey to study the symptomatic characteristics, family history, and pathologic features of colorectal cancer patients. This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.
Interventions
None listed
Sponsors
Wang Guiyu
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Adults aged 18 years and older with a pathologic diagnosis of colorectal cancer; 2. Undergoing surgical treatment of the primary lesion; 3. Voluntary participation of patients.
Exclusion criteria
1. Do not agree to participate in the survey or withdraw informed consent 2. Patients did not receive surgical treatment or did not undergo pathologic examination
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characteristics of clinical symptoms | 2023.12-2024.10 | Comparison of the characteristics of clinical symptoms in patients of different ages; |
| Family history | 2023.12-2024.10 | Comparison of the probability of having a family history in patients of different age stages; |
| Pathological characteristics | 2023.12-2024.10 | Comparison of pathological characteristics of patients at different age stages; |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Risk factors | 2024.09-2024.10 | Analysis of risk factors for stage progression in colorectal cancer patients |
Countries
China
Contacts
Primary ContactYuliuming Wang, Dr.
Outcome results
None listed