MS
Conditions
Brief summary
Traditional physical therapy resisted training for people with MS have been shown to be beneficial; however, their usefulness has been limited by fatigue. The effect of blood flow restriction on strength and other measures of physical function was demonstrated in healthy populations and those with chronic disease. This study may add missing information to the existing literature and suggests directions for research on the effectiveness of BFR training on individuals with relapsing and remitting MS.
Detailed description
Multiple sclerosis patients are characterized by impaired functional capacity which is related to reduce muscle strength affecting predominantly the lower extremity. Resistance training (RT) has proven to be one of the interventions in MS patients showing a consistent and positive effect on muscle strength and on parameters directly related to lower extremity physical function (eg, walking performance and stair negotiation). Training with blood flow restriction (BFR), is an increasingly common clinical intervention among physical therapists over the past decade and consistent with the evidence. It has been investigated in people with neurological disorders including stroke and incomplete Spinal Cord Injuries. Research is limited on the use of BFR for individuals with MS.
Interventions
OTHERstrengthening ex with BFR training
Therapeutic strengthening training with blood flow restriction of trained limb.
OTHERstrengthening ex
Therapeutic strengthening training program for lower extremities.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. Patients were diagnosed with MS by a neurologist according to McDonald's criteria 2010 2. Expanded Disability Status Scale (EDSS) scores ranging from 2.5 to 5.5 . 3. Patient able to walk 100 meters or more. 4. No change within MS specific medication three months from the study. 5. Last Ms Attack from more than two months.
Exclusion criteria
1. Multiple sclerosis patients with other neurological or orthopedic problems. 2. Multiple sclerosis patients with systemic problems (cardiovascular or pulmonary diseases…). 3. Patients with cognitive impairment. 4. Pregnant female patients. 5. Patients in acute relapse stage. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| muscle strength | one week after the end of treatment | measure maximal torque production at a specified velocity of limb movement. measure torque of hip flexors , extensors , knee flexors and extensors |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| gait performance by Two-dimensional (2D) Motion Analysis system | one week after the end of treatment | kinematic analysis of gait (step length , stride length) |
Countries
Egypt
Contacts
Primary ContactHabiba Zienhom
Outcome results
None listed