Burns
Conditions
Brief summary
The study mainly focuses on pain management using 10- or 20mg oxycodone burn wound dressing at Poznan University of Medical Sciences.
Detailed description
Subjects were randomly assigned to one of the two treatment groups, A and B. Patients scheduled for burn surgery will sign written consent pre-operatively about procedural pain management. Group A received 10mg of oxycodone in wound dressing, while those in Group B received 20mg of oxycodone in wound dressing.
Interventions
DRUGOxycodone 10mg
10mg of oxycodone was added to Octenisept in the wound dressing.
DRUGOxycodone 20mg
20mg of oxycodone was added to Octenisept in the wound dressing.
Sponsors
Poznan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* adults scheduled for surgical burn treatment * aged \> 18 years * ASA physical status 1,2 or 3
Exclusion criteria
* opioid abuse * ASA physical status 4, 5
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum morphine concentration level [ng/ml] | Measured on the day of the procedure | Measurement of the serum morphone concentration on the day of the procedure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NRS score | Measured on the day of the procedure | 0- no pain, 10- the worst pain |
Other
| Measure | Time frame | Description |
|---|---|---|
| Dressing morphine concentration [mg/ml] | Measured on the day of the procedure | Evaluation of the morphine dose |
Outcome results
None listed