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Anterior Thoracic Perforating Artery (PATA); Systematization and Applications in Reconstructive Surgery of the Head and Neck

Anterior Thoracic Perforating Artery (PATA); Systematization and Applications in Reconstructive Surgery of the Head and Neck

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06140160
Acronym
PATA-Fix
Enrollment
75
Registered
2023-11-18
Start date
2023-09-19
Completion date
2024-09-19
Last updated
2023-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Thoracic Perforator Artery, Supraclavicular Flap, Upper Aero-intestinal Tract Cancer

Brief summary

The use of cutaneous or fasciocutaneous flaps is daily in reconstructive surgery ENT in patients with cancers of the upper aero-digestive tract (AVDS). Cancers of the oral cavity require reconstructions with thin flaps in order to best preserve the functions of swallowing and phonation via patients' joints. Indeed, the flaps are inert tissues, which can only be mobilized by the residual muscles of the patients' tongue: their lightness and finesse facilitates this mobilization. The use of free flaps is regular but requires micro-surgical skill of the operator as well as a preserved general condition of the patients and appropriate post-operative care. Alternatively, there are some pedicled flaps with the appropriate thickness to reconstruct extensive loss of substances from the oral cavity in a suitable manner: the supraclavicular flap, the suprahyoid flap, the submental flap and the myo-mucosal flap pedicled on the facial artery being more limited in size. The creation of an anterior thoracic fasciocutaneous flap, pedicled on the anterior thoracic perforating artery (PATA) seems to be another suitable therapeutic option. Only one preliminary Chinese study describes it, on only eleven patients. According to the authors, it would offer a wide skin palette (up to 15x10cm). Its long pedicle (on average 9.2cm) would allow a significant axis of rotation so that the flap easily reaches the oral cavity. The authors underline the variability of the origin of this perforator, arising depending on the case from the transverse cervical trunk (9 cases) or from the supraclavicular artery (2 cases), branches of division of the thyro-cervical trunk. However, when the PATA arises from the supraclavicular artery, its interest could be limited because the creation of a PATA perforator flap could compromise the creation of a secondary supraclavicular flap. Thus, this study aims to clarify the feasibility of harvesting the PATA flap in the greatest number of patients. The objective is to study the variations of the anterior thoracic perforating artery necessary for the creation of this flap, by specifying its vascularization territory and its characteristics.

Interventions

PROCEDUREDoppler ultrasound

To carry out an additional measurement using Doppler ultrasound (non-invasive examination). Doppler ultrasound measurements of the diameter and length of the perforating artery using a high-frequency Doppler ultrasound probe following a Doppler ultrasound of the supra-aortic trunks.

Sponsors

mermoz hospital
CollaboratorUNKNOWN
Ramsay Générale de Santé
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient, man or woman over 18 years old, * Patient admitted for an indication for Doppler ultrasound of the supra-aortic trunks (previously prescribed for any medical reason), * Patient having received written information and collection of the non-opposition of the patient to participate in the study, * Patient affiliated or beneficiary of a security regime social.

Exclusion criteria

* Minor patient, * History of cervical surgery, * Patients who have an inaccessible morphology to an exploration of the lower lateral cervical region, high, below and above the right and left clavicle such as the small necks, and/or with dermato-sclerosis, * Patients who do not have the intellectual or physical allowing them to give their consent, * Patient in period of exclusion due to another research still in progress at the time of inclusion, * Refusal to participate in the patient's study, * Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial decision or administrative, * Pregnant, breastfeeding or parturient woman, * Patient hospitalized without consent.

Design outcomes

Primary

MeasureTime frameDescription
Existence of the anterior thoracic perforating artery1 hourexistence of the anterior thoracic perforating artery (PATA) : yes/no
Presence of the anterior thoracic perforating artery1 hourthe presence of the anterior thoracic perforating artery on the left and right,
Origin of anterior thoracic perforating artery1 hourOrigin of anterior thoracic perforating artery : transverse cervical trunk/ supraclavicular artery

Countries

France

Contacts

Primary ContactJean-François Oudet
jf.oudet@ecten.eu0683346567
Backup ContactMarie Hélène Barba
mh.barba@ecten.eu

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026