Chronic Kidney Diseases
Conditions
Keywords
chronic kidney disease, intradialytic aerobic exercise, physical performance
Brief summary
Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.
Detailed description
Uremic myopathy occurs in 60-75% of Chronic Kidney Disease (CKD) patients undergoing hemodialysis, which causes a decrease in muscle strength and physical performance. Increasing dialysis adequacy is beneficial in reducing the impact of uremia on muscles. Intradialytic aerobic exercise in thrice-weekly hemodialysis patients has improved dialysis adequacy and physical performance. This study aims to determine the effect of intradialytic aerobic exercise on improving dialysis adequacy and physical performance in twice-weekly hemodialysis patients.
Interventions
BEHAVIORALAerobic Exercise
Intradialytic aerobic exercise for eight weeks
Sponsors
Universitas Padjadjaran
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Masking description
The sample in this study was determined randomly using a computer; subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program
Intervention model description
Thirty-four participants receiving hemodialysis were randomized to the intervention and control groups.
Eligibility
Sex/Gender
ALL
Age
25 Years to 54 Years
Healthy volunteers
No
Inclusion criteria
* End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate \<15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years * Hemoglobin levels \> 8mg/dl * Mini-Mental State Examination (MMSE) score of ≥24 * Hamilton Depression Rating Scale (HDRS) score \<25
Exclusion criteria
* Received aerobic exercise in the last 3 months * History of hospitalization in the last 3 months * Access for hemodialysis circulation via the femoral vein. * IMT \<18,5 (underweight) dan ≥35 (obese class II) * Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Kt/V | eight weeks | Dialysis adequacy (Kt/V) and physical performance test with a Short Physical Performance Battery (SPPB) were evaluated before and after the intervention |
Countries
Indonesia
Outcome results
None listed