Monitoring of Glycocalyx for Prediction of Complications After Cardiac Surgery

Evaluation de l'utilité du Monitorage du Glycacalyx Pour prédire Les Complications du Patient de Chirurgie Cardiaque

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06136637

Acronym

MOGLYCC

Enrollment

Registered

2023-11-18

Start date

2022-06-01

Completion date

2026-07-01

Last updated

2024-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery

Keywords

Glycocalyx, Microcirculation, Cardiopulmonary bypass, Organ failure

Brief summary

This is a prospective observational study of the evolution of the microcirculation and the sublingual glycocalyx in perioperative cardiac surgery under cardiopulmonary bypass. Our main objective is to evaluate the prognostic value of the variation of the thickness of the perioperative glycocalyx for the occurrence of a major complication in the first 24 hours after surgery.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patient of legal age (age ≥ 18 years) * Patient undergoing scheduled cardiac surgery with cardiopulmoary bypass (CPB) (expected duration of CPB \> 60 min) * Person informed with collection of non-opposition at the latest, the day before the operation - Person affiliated to a social security system

Design outcomes

Primary

Measure	Time frame	Description
Glycocalyx thickness variation	Two hours after the end of cardiopulmonarybypass	Change in glycocalyx thickness between the preoperative period and the postoperative period (2 hours after the end of cardiopulmonary bypass).

Countries

France

Contacts

Primary ContactDemailly Zoé, MD

zoe.demailly@chu-rouen.fr0232882440

Backup ContactDRCI Rouen

0232888265

Outcome results