Clinical Significance of Marginal Acute Inflammation for Stage II Colon Cancer

Presence and Clinical Significance of Marginal Acute Inflammation for Stage II Colon Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06135558

Enrollment

1167

Registered

2023-11-18

Start date

2016-01-30

Completion date

2023-10-30

Last updated

2023-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Inflammation

Brief summary

Marginal acute inflammation would make reporting the serosal involvement of tumors controversial. We aimed to investigate the clinical significance and explore the prognostic value of MAI for stage II localized colon cancer.

Interventions

DIAGNOSTIC_TESTMAI detection

to detect the presence of marginal acute inflammation

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* (1) colon cancer patients with the preoperative staging of stage I-III who lacked distant metastasis; (2) patients who underwent radical resection, with postoperative pathology confirmed as pT3-4N0M0; and (3) complete follow-up information

Exclusion criteria

* (1) patients who received neo-adjuvant therapy; (2) patients with multiple primary colorectal cancer; and (3) patients with a history of malignant tumors

Design outcomes

Primary

Measure	Time frame	Description
DFS	5 year	disease free survival

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026