Diagnosis, Gastric Cancer, Multi-omics
Conditions
Brief summary
In the study, the investigators obtained gastric cancer tissues from 480 gastric cancer patients who had undergone surgery at the Zhejiang Cancer Hospital's biospecimen bank between 2012-2019, and obtained relevant clinical information. The gastric cancer tissues were subjected to transcriptomic, metabolomic and other multi-omics testing, and analyzed for the metabolic changes of gastric cancer, and proposed to discover relevant therapeutic targets.
Interventions
There were no special interventions for the two groups.
Sponsors
Zhejiang Cancer Hospital
Study design
Observational model
CASE_ONLY
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* 18≤age≤80 * Histologically or cytologically confirmed gastric cancer * Undergo surgery for radical or palliative gastric cancer (both open and laparoscopic) * Patients with survival follow-up information
Exclusion criteria
* Two or more kinds of malignant tumors at the same time * Incomplete or missing case information * Preoperative diagnosis of residual gastric cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The differences of the metabolism information | through study completion, an average of 6 months | The differences of the metabolism information between gastric cancer tissues and non-cancerous gastric cancer tissues. These data included Metabolizing enzyme mRNA expression and metabolite content. |
Countries
China
Outcome results
None listed