Skip to content

Observation and Interactions Between Cardio-respiratory and Motor Transitions at the Limits of Moderate Exercise.

Observation et Mise en Relation Des Transitions Cardio-respiratoires et Motrices à la frontière de l'Exercice modéré

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06132724
Acronym
CAREMO
Enrollment
20
Registered
2023-11-15
Start date
2023-12-05
Completion date
2024-06-11
Last updated
2025-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Retraining, Physical Activity, First Ventilatory Threshold, Moderate Intensity Domain, Physiological Transitions, Motricity, Cardiorespiratory, Connected Objects

Brief summary

The goal of this observational study is to learn about physiological transitions around the limit of moderate exercise intensity on cardiac, respiratory and motor modalities, in healthy population. The main questions it aims to answer is: * is it possible to define criteria on cardiac, respiratory and motor modalities to identify transitions? * are those transitions visible on embedded and non-intrusive monitoring equipment? * are those identified transitions somehow connected to first ventilatory threshold (VT1)? Participants will do a sub-maximal effort test on cycloergometer calibrated to make them cross their first ventilatory threshold.

Detailed description

Cycling is a commonly prescribed activity when it comes to physical activities for rehabilitation. Because it is soft and progressive effort, cycling suits well for patients with chronic conditions (diabete, cancer, fibromyalgia, ...) For safety and effectiveness of the activity, it is necessary to prescribe activity at a regular and moderate intensity. This can be achieved by personalizing intensities to match specifically the patient health condition in order to build an efficient and progressive rehabilitation program. Physical activity prescription rely on four pillars: frequency, duration, volume and intensity. While first three pillars are quite easy to regulate,effort intensity is harder to handle on training planning. It is harder to measure, and defining personalized guideline for practice is more complex. It is known that first ventilatory threshold (VT1) is a individualized marker representing the higher limit of moderate intensity effort zone. It makes it an interesting tool for the prescription of intensity for retraining purposes: it guaranties a safe practice, intense enough to make beneficial physiological adaptations for the patient. In this retraining context and with this study, we aim to identify markers of this transition on cardiac, respiratory and motor modalities, with embedded and non intrusive equipment, during a sub-maximal effort test in laboratory.

Interventions

Synchronized signals from cardiac, respiratory and movements non invasive measurements. One acquisition is 20 minutes long, and each subject participate to two sessions, separated by 1 to 15 days.

Sponsors

TIMC-IMAG
CollaboratorOTHER
University Grenoble Alps
CollaboratorOTHER
University Hospital, Grenoble
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
Yes

Inclusion criteria

* Capability to cycle during 20min * No contraindication to cycling at a moderate pace * No acute pathology (less than 2 years old) * No cardiac or respiratory chronic pathology * No locomotive problem on the spine or the lower limbs * No recent injuries (less than 2 months) * Stature compatible with the use of the plethysmography t-shirt

Exclusion criteria

* Pregnant (urine strip test) or breastfeeding women * Persons referred to in articles L1121-5 to L1121-8 of the CSP (protected persons) person deprived of liberty by judicial or administrative decision, person subject to a legal protection measure * Subject being excluded from another study * Subject who reached the ceiling of 4500 euros due to their participation in other studies involving human in the past 12 months

Design outcomes

Primary

MeasureTime frameDescription
Database of physiological signals20 minutesSynchronized signals from embedded and non-intrusive connected devices for cardiorespiratory and motricity measurements and equivalent laboratory measurements during cycling on a cyclo-ergometer

Secondary

MeasureTime frameDescription
Evaluation of the feeling of wearing equipment15 minutesQuestionnaire at the end of each session to assess the comfort / discomfort wearing the equipment used during the test
Criteria for the observation of a respiratory transition6 monthsFeasibility of the transition detection, repeatability of the detection with the respiratory criteria
Criteria for the observation of a cardiac transition6 monthsFeasibility of the transition detection, repeatability of the detection with the cardiac criteria
Criteria for the observation of a motricity transition6 monthsFeasibility of the transition detection, repeatability of the detection with the motricity criteria
Multi-modal prediction of the first ventilatory threshold6 monthsCorrelation with the measurement of ventilatory threshold 1 (VT1)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026