Respiratory Function Impaired, Sarcopenia
Conditions
Keywords
sarcopenia, respiratory force, institutionalized elderly
Brief summary
Objectives: The objectives of this study are to describe the prevalence of respiratory sarcopenia in institutionalized older adults. Methodology: A sample of approximately 120 older adults from 5 residences located in Murcia capital will participate in the study. A prospective observational study will be carried out, with one year of follow-up, with patients who have been diagnosed with respiratory sarcopenia. Sociodemographic and clinical variables, physical function (palm grip, 5STS, 4MGS), respiratory force variables (MIP and PEF) and diaphragmatic ultrasound (thickness, shortening fraction and diaphragmatic excursion) will be measured. Descriptive statistics, univariate and multivariate logistic regression models, Cox proportional hazards model and KaplanMeier curves will be used to analyze the data from the longitudinal study.
Interventions
None listed
Sponsors
Felipe León Morillas
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* To have functional ambulation and/or wheelchair. * preserved cognitive status. * have sufficient ability to Oral occlusion for carrying out respiratory tests.
Exclusion criteria
* presence of respiratory diseases or in treatment of respiratory diseases. * serious orthopedic diseases that interfere with measurements and those with a diagnosis of dementia. * those who present any contraindication for carrying out the procedure will be excluded. * of the respiratory pressure measurement tests, as established in the SEPAR guidelines.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diaphragmatic ultrasound variables | 8 MONTHS | The diaphragmatic ultrasound variables examined will be mobility, thickness and fraction of shortening. For this we will use the Esaote MyLab™ Sigma ultrasound machine (Esaote SpA, Genoa, Italy), with double probe (linear and convex). |
| Sociodemographic | 8 MONTHS | Sociodemographic dates |
| Clinical variables | 8 MONTHS | Clinical variables will be extracted from history clinic |
| Palm grip strength | 8 MONTHS | Palm grip strength will be measured with the digital hand dynamometer (Jamar©). The Participants will remain seated with the shoulder in 0° adduction; elbow flexed 90° and forearm in neutral position. Three attempts will be made and the best value will be chosen |
| 5 SIT TO STAND | 8 MONTHS | The 5STS test measures the time (in seconds) it takes a subject to stop 5 times from a sitting position, as quickly as possible. |
| 4 METRES | 8 MONTS | The gait speed test (4MGS) measures the time it takes to cross a line of 4m at normal speed. |
| Body composition | 8 MONTHS | \- The analysis of body composition will be carried out with the TANITA MC 780-P MA monitor, which provides information on visceral and body fat, skeletal muscle level, BMI and basal metabolism. |
| Respiratoy muscle force | 8 MONTHS | To measure respiratory muscle force, the maximum respiratory pressures will be evaluated in mouth (PIM/PEM). For them we will use an inspiratory and expiratory mouth pressure monitor maximum, a module of the Datapir touch© spirometer (Sibelmed, Barcelona). The measurement will be performed by a previously trained and experienced physiotherapist, following the protocol established by the Spanish Society of Pulmonology (4-SEPAR). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Health results | 8 MONTHS | The health outcome variables that will be recorded over a year will be: infections respiratory diseases, visit to the emergency department, hospitalization, bedridden and/or death. This Information will be extracted from the patient's clinical record. |
Countries
Spain
Outcome results
None listed