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Vestibulo-Ocular Reflex Function in Individuals With Chronic Motion Sensitivity Cross-Sectional Study

Vestibulo-Ocular Reflex Function in Individuals With Chronic Motion Sensitivity Cross-Sectional Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06128707
Enrollment
59
Registered
2023-11-13
Start date
2023-09-30
Completion date
2024-02-01
Last updated
2024-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motion Sickness

Keywords

Chronic motion sensitivity

Brief summary

Chronic motion sensitivity refers to a sensation of unwellness caused by physical or discerned motion and has a prevalence of 28% in the general population and it is more common in women (27.3%) compared to men. The investigators theorize that individuals with chronic motion sensitivity will have an impaired inner ear reflex and will be less physically active. Hence, the purpose of this study is to; 1. Determine whether the function of an inner ear reflex is different between young adults with/without chronic motion sensitivity 2. Assess relationships between reflex function and balance in young adults with/without CMS 3. Assess relationships between physical activity and balance in young adults with/without CMS.

Detailed description

Chronic motion sensitivity (CMS), also known as motion sickness, refers to a sensation of unwellness caused by physical or discerned motion. CMS has a prevalence of 28% in the general population and it is more common in women (27.3%) compared to men. Based on established evidence that individuals with chronic motion sensitivity demonstrate impaired postural stability with vestibular system impairment adjudged to be an inciting stimulus for chronic motion sensitivity, and individuals who practiced more physical and sporting activities have less motion sickness susceptibility than individuals who did not, the investigators theorize that individuals with chronic motion sensitivity will have an impaired inner ear reflex, causing them to be more reliant on other sensory systems like their muscles and joints, and their vision, we also theorize that individuals who are physically active will be less susceptible to chronic motion sensitivity. The purpose of this study is to; 1. Determine whether the function of an inner ear reflex is different between young adults with/without chronic motion sensitivity 2. Assess relationships between reflex function and balance in young adults with/without CMS 3. Assess relationships between physical activity and balance in young adults with/without CMS. Participants between the age of 20 and 40 with and without a self-reported history of chronic motion sensitivity (i.e, experiencing nauseousness and/or dizziness during while using various means of transportation such as, car, train, bus, boat, and airplane and/or, recreational fun-fair rides and/or when exposed to conflicting visual images). Participants will be excluded if they report a medical diagnosis of central nervous system disorder, impaired cervical spine range of motion, migraines, seizure disorder, vestibular dysfunction, or any musculoskeletal dysfunction that can limit their participation in the study.

Interventions

None listed

Sponsors

Loma Linda University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 40 Years

Inclusion criteria

* Age 20-40 * With and without a history of CMS

Exclusion criteria

* CNS disorder * Impaired cervical spine ROM * Migraines * Seizures * Vestibular dysfunction * Musculoskeletal dysfunction * Medications causing dizziness

Design outcomes

Primary

MeasureTime frameDescription
Bertec vision advantage1 dayScores on 4 parametters- Baseline visual acuity (Logarithm of the minimum angle of resolution LogMAR)- A measure of optotype size with lower values signifying smaller optotype size and better vision with the head static, Visual processing time (Mili seconds) this is the time taken to identify the size of the optotype, Dynamic visual acuity (Logarithm of the minimum angle of resolution LogMAR)-A measure of optotype size with lower values signifying smaller optotype size and better vision with the head dynamic, Gaze stability test (Degrees per second), this is the highest speed at which the participant can identify the optotype while the head is moving.
Computerized dynamic posturography with immersion virtual reality1 dayAverage scores under 2 conditions- Condition one- Eye open, Stable platform, Condition 2 Eye open, sway referenced platform. Each condition measured gives a score known as the equillibrum score measured as age matched normative data with higher scores signifying stronger balance , and a lower scores signifying weaker balance

Secondary

MeasureTime frameDescription
International Physical activity questionaire short form1 dayQuestionaire to assess physical activity

Other

MeasureTime frameDescription
Motion sickness susceptibility questionnaire short form1 dayQuestionnaire used to asses motion sickness susceptibility

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026