Adenocarcinoma, Carcinoma, Neoplasms
Conditions
Keywords
Adenocarcinoma, fine-needle aspiration, endoscopic ultrasonography, epidemiology, biobank, DNA tumors
Brief summary
BACAP-2 is a prospective biobank dedicated to the pancreatic adenocarcinoma including clinical data and biological samples from tumor. The aim is to enrich the previous propective collection BACAP in order to support future research projects.
Detailed description
Pancreatic cancer represents the fourth cause of death by cancer in Western countries. In over 90% of cases, it is due to an adenocarcinoma. The only curative treatment for pancreatic cancer remains the surgical exeresis. This one can only be suggested as a curative treatment in only 10 to 15% of cases. Besides, prevention or screening is difficult to set up due to the absence of clearly identified risk factors or groups and to the absence of useful markers for the diagnosis in clinical practice. The research efforts in this area must face a double challenge: saving time while improving the diagnosis period and strengthen the therapeutic equipment. It is important to identify and characterise the new molecular markers applicable for a better diagnosis and/or treatment (especially the response factors to chemotherapy). The present project aims to enrich with fresh tumor tissue and somatic genetic analysis the existing propective collection BACAP in order to support support future research projects on: * the development of new diagnostic tools, * understanding the development of tumors of the pancreas * the development of new therapeutic targets * understanding the response to chemotherapy…
Interventions
Collection of biological samples including whole blood and micro-biopsy from tissue of pancreas
Sponsors
University Hospital, Toulouse
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 120 Years
Inclusion criteria
* Patient with pancreatic mass syndrome explored by ultrasound endoscopy with cytopuncture or * Patient with pancreatic mass syndrome explored by an abdominal scanner with and without injection of product contrast and/or puncture of the mass or secondary lesions by radiological route or * Patient with pancreatic adenocarcinoma proven histologically and/or cytologically
Exclusion criteria
* Patient with a pancreatic tumor whose analysis histological is not an adenocarcinoma * Pregnant or breastfeeding patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Enrichment of prospective BACAP collection | 5 years | This collection is coming to enrich the prospective BACAP collection of fresh tumor tissue and/or fixed from the micro-biopsy under endoscopic ultrasound |
Countries
France
Contacts
CONTACTBarbara BOURNET, MD, PhD
CONTACTCindy CANIVET, PhD
PRINCIPAL_INVESTIGATORBarbara BOURNET, MD, PhD
University Hospital, Toulouse
Outcome results
None listed