Coronary Artery Disease
Conditions
Brief summary
The objective of the Zhongshan Hospital CONCORDE Registry is to evaluate utility, diagnostic value, and clinical outcomes of coronary physiological indices in an all-comers population of patients with suspected coronary artery disease referred to invasive coronary angiography in order to further inform patients and health care providers about which technologies are most effective and efficient in the diagnosis and management of coronary artery diseases.
Detailed description
CONCORDE registry offers a comprehensive pressure and/or flow measurements, as well as angiography-derived functional assessment of coronary. Patient treatment was at the operator's discretion at the time of the invasive procedure. A standardized data collection sheet was used and data were extracted from electrical medical history according to standardized definition of patient's baseline characteristics, clinical outcomes, and physiologic data.
Interventions
Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Resting full-cycle ratio, Coronary Flow Reserve, Microvascular resistance
Sponsors
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* suspected coronary artery disease * referred to invasive coronary angiography
Exclusion criteria
* hemodynamic instability
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major adverse cardiac events (MACE) | 5 years | Cumulative incidence of a composite of any death, any myocardial infarction, or any ischemia-driven revascularization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Target vessel failure (TVF) | 5 years | Cumulative incidence of a composite of cardiac death, target-vessel related myocardial infarction, or target-vessel revascularization |
| Individual components of MACE and TVF | 5 years | Cumulative incidence of the individual components of MACE and TVF |
Countries
China
Outcome results
None listed