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Brain Health Virtual Reality Study

Interventions to Promote Brain Health Virtual Reality Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06124339
Enrollment
150
Registered
2023-11-09
Start date
2023-08-08
Completion date
2029-02-01
Last updated
2026-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging, Aging Problems, Cognition Disorders in Old Age, Cognitive Change, Cognitive Decline, Memory Disorders, Memory Disorders in Old Age, Memory Disorder, Spatial, Memory Impairment, Memory Loss, Mild Cognitive Impairment

Keywords

Virtual Reality, technology, intervention, exercise, cycling, memory, brain health, aging

Brief summary

The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa. The overarching goal of this trial is to use a novel virtual reality (VR) based intervention that simultaneously engages physical and cognitive activity aimed at improving brain health and cognition in older adults. The investigators will compare 3 types of interventions: physical activity, VR cognitive activity, and combined VR physical and cognitive activity over 16 weeks to evaluate physical and brain health changes.

Interventions

BEHAVIORALPhysical Activity

There will be three sessions a week over the course of 16 weeks.

BEHAVIORALCognitive Activity (VR)

There will be three sessions a week over the course of 16 weeks.

BEHAVIORALPhysical and Cognitive Activity

There will be three sessions a week over the course of 16 weeks.

Sponsors

University of California, San Diego
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
50 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

1. 50-85 years of age 2. Fluent in English 3. Can safely ride a stationary bike

Exclusion criteria

1. Dementia 2. History of a neurological disorder 3. Severe sensory deficits 4. Inability to perform intervention (e.g., inability to cycle safely) 5. Contraindications to MRI scan (e.g., pacemaker) 6. Fear of needles/ blood 7. Prior history of fainting due to sight of needles of blood

Design outcomes

Primary

MeasureTime frameDescription
MST memory performance16 WeeksWith the study's primary focus on hippocampal function, we will use the Mnemonic Separation Task (MST), a hippocampus-dependent discrimination test of similar objects, as our primary cognitive outcome. The MST is a memory task designed to heavily tax memory processes for making fine discriminations between highly similar objects or unrelated objects.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 16, 2026