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Artificial Intelligence (AI) Empowered Smile Simulations: Do They Accurately Predict Actual Post Treatment Outcomes

Artificial Intelligence (AI) Empowered Smile Simulations: Do They Accurately Predict Actual Post Treatment Outcomes

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06123585
Enrollment
24
Registered
2023-11-09
Start date
2018-01-01
Completion date
2020-07-05
Last updated
2023-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion

Brief summary

The aim of the present study is to assess the predictability of Invisalign® SmileView™ for digital AI smile simulation in comparison to actual smile treatment outcomes, using various smile assessment parameters.

Interventions

OTHERInvisalign® SmileView™

Pretreatment smiles were captured using the Invisalign® SmileView™ to simulate their new smiles before treatment was started.

OTHERInvisalign aligners

Patients were then treated using upper and lower Invisalign aligners with average treatment time of 12±3 months.

Sponsors

Nourhan M.Aly
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* healthy systemic condition with no chronic diseases * no previous orthodontic treatment * adequate oral hygiene * a healthy periodontium.

Exclusion criteria

* chronic diseases * previous orthodontic treatment * poor oral hygiene * periodontal diseases

Design outcomes

Primary

MeasureTime frameDescription
Smile linethrough study completion, an average of 1 yearThe extent of the vertical tooth display on smiling or the elevation of the upper lip in relation to the maxillary incisors. Three types of smile lines have been described- high, average, and low. A high smile shows the maxillary anterior teeth along with a significant amount of gingiva, an average smile shows maxillary anterior teeth with only interproximal gingiva, and a low smile typically shows less than two-thirds of the maxillary anterior teeth
Smile arcthrough study completion, an average of 1 yearThe relationship between the curvature of the maxillary anterior teeth and upper border of the lower lip. It is defined by drawing a line along the maxillary central incisal edges to the cusp tips of maxillary canines, which is related to another line drawn across the superior border of the lower lip. In subjects whose maxillary teeth are covered by lower lip, smile arc is designated as not available. Three types of smile arcs have been described- parallel to the teeth (when the two lines follow the same curvature) also called a consonant smile, and a non-consonant smile, if the two lines are not parallel. A non-consonant smile can either be straight (with flatter curvature of the maxillary anterior teeth in relation to the lower lip) or reverse (when the maxillary anterior teeth form a reverse curve in relation to lower lip).
The most posterior teeth displayedthrough study completion, an average of 1 yearSmiles are categorized as displaying teeth up to the canines, first premolars, second premolars, or the first molars. A tooth is counted when more than half of its surface is visible.
The philtrum heightthrough study completion, an average of 1 yearDistance measured in millimeters from subspinale (the base of the nose at the midline) to the most inferior portion of the upper lip on the vermilion tip beneath the philtral columns
Commissure heightthrough study completion, an average of 1 yearDistance measured in millimeters from a line constructed from the alar bases through subspinale and then from the commissures perpendicular to this line. The differential lip growth exhibits the difference in height in philtrum and commissural height in adolescents.
Smile width/Inter-commissure widththrough study completion, an average of 1 yearThe distance (mm) from outer commissure to outer commissure on smile in millimeters.
Smile indexthrough study completion, an average of 1 yearThe ratio between the horizontal smile width and the vertical smile height during smiling (smile width/smile height).
Maxillary inter-canine widththrough study completion, an average of 1 yeardistance from the distal aspect of the right canine to the distal aspect of the left canine in millimeters
Buccal corridorthrough study completion, an average of 1 yearIt is the space created between the buccal surface of the posterior teeth and the lip corners when the patient smiles. Orthodontists often refer to buccal corridors as negative spaces. The buccal corridor is measured from the mesial line angle of the maxillary first premolars to the interior portion of the commissure of the lips. Moore et al \[16\]. have previously quantified a buccal corridor of 28% as medium-narrow, 15% as medium, 10% as medium-broad, and 2% as broad smile fullness
Amount of lower incisor showthrough study completion, an average of 1 yearThe amount of lower incisor display which can be categorized into either 1) No show of lower incisors during smiling, 2) partial lower incisor exposure or 3) full length lower incisor exposure.

Countries

United Arab Emirates

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026