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Impact of Eating Beans on Metabolism

The Influence of the Resistant Starch and Protein Content of Pulses on Substrate Oxidation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06123208
Enrollment
36
Registered
2023-11-08
Start date
2023-10-30
Completion date
2025-08-15
Last updated
2025-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight

Brief summary

The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.

Detailed description

The objective of this project is to test whether consuming a whole food that naturally contains resistant starch (RS), such as pulses, increases fat oxidation. The primary hypothesis is that consuming a RS-rich meal in which the RS is derived from a whole food (i.e., pinto beans, pinto bean flour) will increase postprandial fat oxidation to a greater extent than consuming a meal low in RS but containing the same amount of energy and macronutrient content.

Interventions

OTHERWhole cooked pinto bean

Meal comprised of whole cooked pinto beans

Meal comprised of pinto bean flour

OTHERControl

Control meal

Sponsors

USDA Grand Forks Human Nutrition Research Center
Lead SponsorFED

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* BMI \>18.5 or \<30 kg/m2 * Ability to understand and sign the consent form * Ability of transportation (i.e., participants must be able to provide their own transportation to the Grand Forks Human Nutrition Research Center) * Non-smoking or use of other tobacco products, including e-cigarettes * Not taking steroid-based medications; not planning to or currently attempting to gain or lose weight * All females of childbearing age must be on birth control for a minimum of 3 months prior to start of study

Exclusion criteria

* Inability or unwillingness to consume any food item in the test meals * More than a 10% change in body weight within the past 2 months * Participation in a weight loss diet/exercise program * Current or planned pregnancy * Lactation * Uncontrolled hypertension (systolic \>160 mmHg or diastolic \>100 mmHg) * Diagnosed cardiovascular, pulmonary, skeletal and metabolic diseases * Fasting glucose \> 100 mg/dL or non-fasting (1-2 hours after eating) \>140 mg/dL * Using medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants) * Non-English speaking

Design outcomes

Primary

MeasureTime frameDescription
Acute effects of consuming processed pulse-based food products on substrate utilization5 hours after meal consumptionThe effect of consuming whole beans or bean-derived flour on the use of fat, carbohydrate, and protein for energy will be determine using whole room calorimetry. Fat, carbohydrate, and protein oxidation will be calculated as an absolute amount of grams per day and as a percentage of energy expenditure.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026