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Mesotherapy in the Treatment of Chronic Migraine

The Effectiveness of Mesotherapy (Lidocaine and Proxicam) in the Treatment of Chronic Migraine

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06118190
Enrollment
27
Registered
2023-11-07
Start date
2019-01-01
Completion date
2023-10-29
Last updated
2023-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Migraine, Headache

Keywords

Mesotherapy, Chronic Migraine, pain, muscle, headache

Brief summary

Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain.

Detailed description

Migraine is one of the types of headaches. For the diagnosis of chronic migraine, the headache must last more than 15 days. Nerve blocks, oral medication and neuromodulation are recommended for migraine treatment.Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain. This study was planned to show the effectiveness of mesotherapy in patients with migraine.

Interventions

DRUGLidocain

All participants treated with procaine and lidocaine injection for treatment.

Sponsors

Kanuni Sultan Suleyman Training and Research Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Masking description

open label

Intervention model description

Retrospective analysis of the group that received treatment

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

\- Clinical diagnosis of chronic migraine disease

Exclusion criteria

* Infection disease * Thyroid disease * Anemia disease * Systemic disease

Design outcomes

Primary

MeasureTime frameDescription
Visual Analog Scale (VAS)BaselineVAS rates pain on a scale of zero to 10. It is explained to the participant that 10 points means unbearable pain, zero points means no pain, and the patient is asked to rate his pain between zero and ten. Higher scores indicate increased pain severity
The frequency of painful days per monthBaselineThe participant is asked how many days she/he feels pain in a month.Higher numbers indicate increased frequency of painful days

Secondary

MeasureTime frameDescription
Duration of attack per monthBaselineThe participant is questioned about how long each attack lasts within a month. Increased periods indicate prolonged symptom duration.
the number of analgesic per monthBaselineThe participant is asked how many times he/she uses analgesic medication in a month. Higher numbers indicate an increased need for medical treatment

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026