Effect of Adding Zirconium Oxide Nanoparticles to Printable Implant Overdenture

Effect of Adding Zirconium Oxide Nanoparticles to Printable Implant Overdenture Acrylic Resin Base Material. Clinical Comparative Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06116877

Enrollment

Registered

2023-11-03

Start date

2022-03-03

Completion date

2023-08-11

Last updated

2023-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prosthesis Durability

Brief summary

This clinical study will be conducted to evaluate and compare non-modified printable acrylic resin base material and modified printable acrylic resin base material with zirconia oxide nanoparticles for a 2-implant retained complete overdenture regarding:Surface roughness; microbiological assessment of denture base microbiological analysis peri-implant soft tissue health around used implants

Interventions

PROCEDUREimplant supported overdenture

mandibular 2-implant retained overdenture of non-modified printable acrylate resins base material with Zirconium oxide nanoparticles

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

45 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* 1\. Patients are healthy, free from any systemic diseases relating to bone resorption such as uncontrolled diabetics or osteoporosis. This will be achieved through medical history and clinical examination by physician. 2\. They will have completely edentulous jaws for at least 1 year. 3. They will be of angle's class I maxillo-mandibular relationship and have upper and lower completely edentulous arches. 4\. Residual alveolar ridges covered with healthy firm mucosa. 5. All included patients will have sufficient available length and width of mandibular bone to accommodate conventional implant. (At least 5 mm buccolingual width and 12 mm vertical height of bone.

Exclusion criteria

* Patients with chronic systemic diseases that affect bone metabolism * Uncontrolled diabetic patients * Patients with TMJ dysfunction * Smokers

Design outcomes

Primary

Measure	Time frame	Description
Surface roughness	one year	Surface roughness: will be evaluated using profilometer device
Microbiological assessment	one year	Microbiological assessment of denture base surface microbiological analysis
Peri-implant soft tissue health	one year	was evaluated using scores for plaque and gingival bleeding

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026