Pneumoperitoneum, Renal Injury
Conditions
Keywords
laparoscopy, NIRS, N-GAL
Brief summary
The investigators aimed to show the renal damage caused by increased intra-abdominal pressure in laparoscopic surgeries and to investigate whether its reflection on NIRS would be clinically effective.The main question it aims to answer are: Does pneumoperitoneum cause renal damage? NRS monitoring will be performed in patients undergoing laparoscopic surgery. Preoperative and postoperative blood tests will be performed at certain hours. N-GAL, urea and creatinine values will be recorded.
Detailed description
Renal NIRS monitoring will be performed in patients undergoing laparoscopic cholecystectomy surgery. Age, gender, BMI, ASA scores, hemogblin/hematocrit values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. . Before the general anesthesia is performed, the renal tissues of the patients will be visualized by ultrasound, the skin-renal cortex distances will be measured, and suitable patients will be included in the study. Basal rSO2 values will be recorded by placing NIRS probes under the 10-11. intercostal space in the bilateral posterior lateral flank region.
Interventions
DEVICENIRS
Renal perfusion will be evaluated with NIRS
Sponsors
Diskapi Yildirim Beyazit Education and Research Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Patients who undergoing elective laparoscopic cholecystectomi surgery lasting longer than 60 minutes * BMI:18-25 * skin-renal cortex distance measured less than 4 cm on ultrasound * ASA I-III
Exclusion criteria
* patient who did not give consent * patient who had renal operation before, * infection, abscess, catheter in the perirenal region * hemodynamically unstable patients, * patients with renal pathology and abnormal kidney function tests, * emergency cases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of renal damage caused by pneumoperitoneum with N-GAL by blood test | During laparoscopic cholecystectomy operation and within 24 hours postoperative | Taking a blood test to evaluation N-GAL |
| Evaluation of renal damage caused by pneumoperitoneum with urea/creatinin by blood test | During laparoscopic cholecystectomy operation and within 24 hours postoperative | Taking a blood test to evaluation urea/creatinine values |
Countries
Turkey (Türkiye)
Contacts
Primary ContactSavaş Altınsoy, MD
Outcome results
None listed