Necrotic Pulp, Post Operative Pain
Conditions
Brief summary
The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.
Detailed description
Clinical compare the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction when used as root canal irrigant in necrotic pulp. The post operative pain will be recorded using Numerical rating scale, and the bacterial load reduction will be measured by Bacterial counting using agar culture technique.
Interventions
OTHERVachellia Nelotica
As a root canal irrigant (herbal)
OTHERsodium hypochlorite
As a root canal irrigant
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
1. Systemically healthy patient (ASA I, II). 2. Age between 20 and 40 years. 3. Male or female. 4. Patient who is able to sign and comprehend the pain scale (committed patient). 5. Mandibular single rooted premolars having the following criteria: * With single root canal. * Diagnosed clinically with pulp necrosis. * Absence of spontaneous pulpal pain. * Positive pain on percussion denoting apical periodontitis. * Slight widening of periodontal space or peri-apical radiolucency smaller than 3 mm (0-2mm).
Exclusion criteria
1. Medically compromised patients (ASA III or IV). 2. Teeth with: * Immature roots. * Vital pulp tissues. * Association with swelling. * Acute peri-apical abscess or acute exacerbation of a chronic abscess. * Mobility Grade II or III. * Previously accessed or endodontically treated. * Deep periodontal pockets more than 4 mm. * Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions. 3. Patients who could not interpret the NRS. 4. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women will be also excluded. 5. History of intolerance to NSAIDs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| post operative pain. | At 6, 12, 24, and 48 hours postoperatively (post instrumentation and post obturation) | non=0, mild=1-3, moderate4-6, sever=7-10. Measured and reported by Numerical Rating Scale (NRS). Minimum value=0, maximum value=10, the higher score or value mean a worse outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bacterial load reduction | 1 hour. First sample (S1) will be taken pre-intervention (before chemo-mechanical preparation) and the second sample (S2) will be taken immediately after the intervention (after completion of chemo-mechanical preparation) on the same visit. | Bacterial counting using agar culture technique. |
Contacts
Primary ContactGozlan FS Mohamed
Backup ContactGozlan Fouad
Outcome results
None listed