Alcohol Use, Unspecified
Conditions
Brief summary
The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time. Eligible youth will be invited to come in for a "Participation Day," during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.
Interventions
BEHAVIORALMotivational Interviewing (MI)
Motivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior change.
Sponsors
UConn Health
University of Texas
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 24 Years
Healthy volunteers
Yes
Inclusion criteria
* within the specified age range * agree to be contacted for the 3, 6, and 12 month follow ups * provide fully informed consent
Exclusion criteria
* left-handed * evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics) * loss of consciousness ≥ 2 minutes * other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood oxygen level dependent (BOLD) response synchrony | Baseline | Mean BOLD time series will be obtained for each region of interest (ROI) during peer-directed change talk trials and temporally aligned across dyad participants. Inter-brain synchrony will be quantified using z-transformed GLM β-weights within ROIs between the BOLD time series of dyad members. |
| BOLD response synchrony association with behavior change (past month alcohol use days) | 12 Months | Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 12 month follow up. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BOLD response synchrony association with behavior change (past month alcohol use days) | 3 Months | Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 3 month follow up. |
Countries
United States
Contacts
CONTACTKaren Hudson, MCR
PRINCIPAL_INVESTIGATORSarah W. Feldstein Ewing, PhD
UConn Health
PRINCIPAL_INVESTIGATORFrancesca Filbey, PhD
University of Texas
Outcome results
None listed