Desmoid Tumors
Conditions
Keywords
Desmoid tumors, Fibromatosis, Invasive tumors, Radiotherapy, Cryoablation
Brief summary
Desmoid tumors, also called aggressive fibromatosis, are rare, locally invasive tumors with no potential for metastasis. The incidence is approximately 2 to 4 per million per year in the general population. The watch and wait policy is the standard of care for newly diagnosed patients in Europe. Patients who progress have first-line medical treatment, surgery is no longer the treatment because there is a high rate of recurrence (\> 60%) and radiotherapy is not very suitable because the patients are often young and the tumors are large. Cryoablation seems to be an effective therapeutic option that should be evaluated.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patient (≥18 years old) * Having undergone cryoablation for an advanced desmoid tumor refractory to medical treatment * Having not expressed their opposition, after being informed, to the reuse of their data for the purposes of this research.
Exclusion criteria
* Subject who expressed their opposition to participating in the study * Patient already included in another ongoing study * Subject under guardianship or curatorship * Subject under safeguard of justice
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival assessed using RECIST(Response evaluation criteria in solid tumors) criteria | at 6 months after cryoablation |
Countries
France
Contacts
Primary ContactPierre AULOGE, MD
Outcome results
None listed