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A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06112769
Enrollment
64
Registered
2023-11-01
Start date
2023-10-29
Completion date
2024-01-31
Last updated
2025-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic

Keywords

Internal jugular vein, propofol, hypotension, hemodynamic

Brief summary

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Detailed description

1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV 2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed. 3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Interventions

None listed

Sponsors

Affiliated Hospital of Jiaxing University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* age over 60 years * American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ * Surgery with radial artery puncture * Propofol induction

Exclusion criteria

* BMI≥30kg/m2 * People with short necks; * Previous hypotension (systolic blood pressure \<90mmHg or mean arterial pressure \<65mmHg) * Previous poorly controlled hypertension * Cardiac insufficiency , EF value\<50% * Upper limb deep vein thrombosis * History of radiotherapy or neck surgery * Inability to maintain a supine position for necessary measurements * Mechanical ventilation status or inability to take deep breaths patients * gastrointestinal surgery * patients allergic to propofol.

Design outcomes

Primary

MeasureTime frameDescription
IJVV during deep inhalation1 yearIJVV (%) = (diamax - diamin)/\[(diamax + diamin)/2\] × 100

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026