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Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia

Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06112236
Enrollment
250
Registered
2023-11-01
Start date
2023-02-17
Completion date
2027-03-31
Last updated
2023-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypophosphatemia

Brief summary

The aim of this study is to generate evidence regarding hypophosphatemia after iron infusion in lung transplant recipients in context of anemia and/or iron deficiency.

Interventions

OTHERno intervention

no intervention

Sponsors

University of Zurich
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* lung transplant recipient * treated at the University Hospital Zurich between 2015 until 2022

Exclusion criteria

* Denied general consent

Design outcomes

Primary

MeasureTime frameDescription
Change of serum phosphate levelBaseline and up to 90 days after iron infusionChange of serum phosphate level before and after iron infusion

Secondary

MeasureTime frameDescription
Change of hemoglobinBaseline and up to 90 days after iron infusionChange of hemoglobin level before and after iron infusion
Change of mean corpuscular volume (MCV)Baseline and up to 90 days after iron infusionChanges of serum MCV level before and after iron infusion
Change of mean corpuscular hemoglobin (MCH)Baseline and up to 90 days after iron infusionChange of serum MCH level before and after iron infusion
Change of serum magnesiumBaseline and up to 90 days after iron infusionChange of serum magnesium level before and after iron infusion
Change of urin phosphate levelBaseline and up to 90 days after iron infusionChange of urin phosphate level before and after iron infusion
Change of serum albuminBaseline and up to 90 days after iron infusionChange of serum albumin level before and after iron infusion
Complications after iron infusion2015-2022Number of patients with complications due to hypophosphatemia after iron infusion (Hospitalization, hypoxia, fracture due to hypophosphatemia)
Predictorsbaseline and up to 90 days after iron infusionAnalysis of possible predictors for the decrease of serum phosphate levels after iron infusion
Therapeutic management2015 to 2022Descriptive analysis of therapeutic management of hypophosphatemia after iron infusion
Change of serum and urin calciumBaseline and up to 90 days after iron infusionChange of serum and urin calcium level before and after iron infusion

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 26, 2026